Page 144 - Screening for Cervical Cancer: Systematic Evidence Review
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Appendix C.  Evidence Tables



               Evidence Table 3A.  Performance of HPV Testing for Screening (cont'd)

                Source: Author,      Study Design &
                     Year            Characteristics            Interventions        Location & Time Period
               Womack et al.,   Diagnostic test evaluation   HPV testing using Hybrid   Chitungwiza and the greater
                     62
               2000b            for primary screening    Capture II assay, probe B   Harare area, Zimbabwe, Oct
                                                         (13 high risk subtypes) and  1996-1997
                                                         assessment of outcome by
                                                         biopsy/ colposcopy for all
                                                         participants

                                                         Testing of HPV viral load
                                                         using relative light unit ratios

                                                         Colposcopists blinded to
                                                         results of HPV tests and
                                                         visual inspection






               Wright et al.,   Diagnostic test evaluation   HPV testing using Hybrid   Environs of CapeTown,
               2000 64          (HPV) among population   Capture II assay in both   South Africa
                                also screened using  Pap,  patient collected and   1998-1999
                                direct visual inspection,   physician collected
                                cervicography  and       specimens
                                assessment of outcome by
                                biopsy/ colposcopy

                                Abnormals on any test
                                referred for verification

































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