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                                 Introduction


                                 Robert Garner


      There is a well-founded science-base for understanding addiction as a
      chronic, and for many, recurring disease characterized by compulsive
      drug seeking and use.  An abundance of research has consistently
      shown that chronic drug use affects the brain in fundamental ways
      often remaining long after the drug using behavior has stopped.
      Research science has also increased our understanding about the very
      nature of drug addiction, which has created new inroads for dramatic
      improvement in treatment approaches.

      Using brain-imaging technologies, science can demonstrate the
      biological basis for addiction and has provided the basis for a
      biopsychosocial perspective of chemical dependency.  From this
      knowledge we are now able to accept that for some addicted persons,
      medications are critical to treat drug-induced brain deficits in order to
      help sustain a symptoms-free lifestyle.

      In much the same way that research provided for medications
      development used for other chronic diseases, such as hypertension,
      diabetes, and asthma, addiction medicine is following the same course.
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