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              Guidelines for the treatment of malaria – 2  edition


            Declaration of interests
            Participants of the Technical Consultation on the review of the WHO Guidelines for the
            Treatment of Malaria and the external expert reviewers of the guidelines reported relevant
            interests, in accordance with WHO procedures. These were discussed extensively by the
            committee. Although it was considered that none of these declared interests had any
            direct relevance to the deliberations and recommendations of the meeting, those panel
            members with declared interests were excluded from the GRADE and recommendations
            sub-committee and the guidelines drafting sub-committee. The declared interest, as per
            WHO regulations, was cleared through the Legal Department of WHO.

            Dr N. Valecha reported serving as an investigator for clinical trials supported by the
            Medicine for Malaria Venture (MMV), the Drugs for Neglected Diseases initiative (DNDi)
            and Ranbaxy Laboratories Limited. There were no monetary benefits and no conflicts
            with the subject of this review.
            Dr L. Sluscker reported having collaborated with the Kenya Medical Research Institute
            on a study of paediatric Coartem®. The CDC did not receive funds from the manufacturer
            (Novartis Pharma AG).
            Professor A. Bjorkman reported having participated in a study on paediatric Coartem®
            sponsored by Novartis Pharma AG.
            Dr K. Barnes reported being a grants co-recipient from the Global Fund to Fight AIDS,
            Tuberculosis and Malaria (GFATM), the Bill and Melinda Gates Foundation (BMGF)
            and the UK Department for International Development (DfiD) to evaluate antimalarial
            medicines.

            Dr G. Mokuolu reported being a co-investigator in a multi-centre study comparing
            intravenous artesunate and quinine for the treatment of severe malaria in African
            children. The study is funded by Oxford University, the United Kingdom.
            Dr F. ter-Kuile reported grant income from two not-for-profit project drug developers
            (MMV and DNDi).  He also received a previous grant from Novartis Pharma AG, and
            is currently serving on the Coartem® advisory board for Novartis.
            Dr D. Terlouw reported receiving research funding from an organization that supports
            the development of drugs for tropical diseases, including malaria.
            All other members of the committee reported no interests.











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