Page 43 - 78 glossary of hivaids-related terms_opt

approved by the FDA, they must go through Phase I and II dose-
ranging studies.
See Also: Clinical Trial
Phase I Trial
Phase II Trial
D

Dose-Response Relationship
The relationship between the dose of a drug and its corresponding
effect on the body. If a drug exhibits a dose-response effect, it
means that as the dose increases, so does the effect.

DOT
See: Directly Observed Therapy

Double-Blind Study
A clinical trial design in which neither the participants nor the
study staff know which individuals are receiving the experimental
treatment and which are receiving a placebo (or another control
therapy). Double-blind trials produce more objective results,
because the expectations of the study staff and the participants do
not affect the outcome.
See Also: Controlled Trial

DRESS
See: Drug Rash with Eosinophilia and Systemic Symptoms

Drug Antagonism
An interaction between two or more drugs in which one drug blocks
or reverses the effect of another drug.

Drug Class
A group of drugs that share common properties, such as
mechanisms of action.

Drug Concentration
See: Concentration

HIV/AIDS Glossary 41