Page 42 - 78 glossary of hivaids-related terms_opt

by the HIV/AIDS epidemic; to increase basic knowledge of the
pathogenesis, natural history, and transmission of HIV disease;
and to support research to promote HIV detection, treatment, and
prevention.
See Also: National Institute of Allergy and Infectious Diseases (NIAID)
D
National Institutes of Health (NIH)

DNA
See: Deoxyribonucleic Acid

Dorsocervical Fat Pad
A type of lipodystrophy (a problem in the way the body produces,
uses, and distributes fat) in which fatty tissue builds up on the upper
back and neck. It most often occurs in HIV-infected people as a
result of PI or NRTI drug treatment. This fat buildup, also known as
buffalo hump, may be associated with other metabolic side effects,
such as high insulin levels.
See Also: Lipodystrophy
Body Habitus Changes

Dosage
The scheduled administration of individual drug doses, usually
expressed as a quantity per unit of time. For example, a prescribed
drug dosage may be 200 mg per day (but the individual dose could
be 100 mg in the morning and 100 mg in the evening).

Dose
The measured amount of a therapeutic agent that is taken at
one time, or the total amount taken during one time period. For
example, a single dose of 100 mg may be taken at one time, or
a total dose of 1,000 mg may be taken during one 5-day
treatment period.
See Also: Dosage

Dose-Ranging Study
Clinical trial in which different doses of a drug are tested to
determine which is the safest and most effective. Before drugs are

40 HIV/AIDS Glossary