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and parasites that cause diarrheal symptoms in otherwise healthy
people may cause more severe, prolonged, or recurrent diarrhea
in people with HIV or AIDS.
Directly Administered Antiretroviral Therapy (DAART) D
Method of ensuring that a person takes anti-HIV drugs as
prescribed. DAART requires that a caregiver directly observe the
patient ingest the anti-HIV drugs to increase adherence to the
treatment plan.
See Also: Adherence
Directly Observed Therapy (DOT)
Directly Observed Therapy (DOT)
A treatment strategy to ensure adherence, in which a health care
provider or other observer watches a patient take each dose of a
drug. This strategy is used with diseases like tuberculosis (TB) and
HIV infection, in which adherence is important for effective treatment
and to prevent emergence of drug resistance.
See Also: Adherence
Discordant Couple
A pair of long-term sexual partners in which one person is
infected with a sexually transmitted infection (such as HIV) and
the other is not.
Disseminated
Widely dispersed across the entire body. In immunocompromised
people, such as those with AIDS, coinfections (e.g., cryptococcosis,
histoplasmosis, Mycobacterium avium complex, etc.) may become
disseminated and spread through the bloodstream to infect lymph
nodes, bone marrow, liver, spleen, spinal fluid, lungs, and the
intestinal tract.
Division of Acquired Immunodeficiency Syndrome (DAIDS)
A division of the National Institutes of Health’s (NIH’s) National
Institute of Allergy and Infectious Diseases (NIAID). DAIDS was
formed in 1986 to address the national research needs created
HIV/AIDS Glossary 39