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and parasites that cause diarrheal symptoms in otherwise healthy
           people may cause more severe, prolonged, or recurrent diarrhea
           in people with HIV or AIDS.

        Directly Administered Antiretroviral Therapy (DAART)               D
           Method of ensuring that a person takes anti-HIV drugs as
           prescribed. DAART requires that a caregiver directly observe the
           patient ingest the anti-HIV drugs to increase adherence to the
           treatment plan.
           See Also:  Adherence
                    Directly Observed Therapy (DOT)

        Directly Observed Therapy (DOT)
           A treatment strategy to ensure adherence, in which a health care
           provider or other observer watches a patient take each dose of a
           drug. This strategy is used with diseases like tuberculosis (TB) and
           HIV infection, in which adherence is important for effective treatment
           and to prevent emergence of drug resistance.
           See Also: Adherence

        Discordant Couple
           A pair of long-term sexual partners in which one person is
           infected with a sexually transmitted infection (such as HIV) and
           the other is not.

        Disseminated
           Widely dispersed across the entire body. In immunocompromised
           people, such as those with AIDS, coinfections (e.g., cryptococcosis,
           histoplasmosis, Mycobacterium avium complex, etc.) may become
           disseminated and spread through the bloodstream to infect lymph
           nodes, bone marrow, liver, spleen, spinal fluid, lungs, and the
           intestinal tract.

        Division of Acquired Immunodeficiency Syndrome (DAIDS)
           A division of the National Institutes of Health’s (NIH’s) National
           Institute of Allergy and Infectious Diseases (NIAID). DAIDS was
           formed in 1986 to address the national research needs created


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