Page 15 - 78 glossary of hivaids-related terms_opt

Approved Drug A
In the United States, the Food and Drug Administration (FDA) must
approve a drug before it can be marketed and sold to the public.
The approval process involves several steps, including laboratory
and animal studies, clinical trials for safety and efficacy, filing of
a New Drug Application (NDA) by the manufacturer of the drug,
FDA review of the application, and FDA approval/rejection of the
application.
See Also: New Drug Application (NDA)

ARC
See: AIDS-Related Complex

Area Under the Curve (AUC)
A measure of how much drug reaches a person’s bloodstream in a
given period of time (usually the time between each dose or within
24 hours of a dose). The AUC is calculated by plotting the drug’s
blood levels on a graph at different times during the set period
to form a curve. The area under this curve reflects the total drug
exposure in the set time period.

Arm
Any of the treatment groups in a clinical trial. Most clinical trials have
two arms, but some have three or even more. Each arm receives a
different treatment or placebo.
See Also: Clinical Trial
Placebo

ARS
See: Acute Retroviral Syndrome

ART
See: Antiretroviral Therapy

Arthralgia
Joint pain with additional symptoms such as heat, redness,
tenderness to touch, loss of motion, or swelling.

HIV/AIDS Glossary 13