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Treatment Failure
A broad term that describes failure of an anti-HIV treatment to
adequately control HIV infection. The three types of HIV treatment
failure are virologic, immunologic, and clinical failure. Factors
that contribute to treatment failure include poor adherence, drug
resistance, and drug toxicity.
See Also: Virologic Failure
Immunologic Failure
Clinical Failure
Treatment-Naive
A term used to describe HIV-infected individuals who have never
taken anti-HIV drugs.
See Also: Treatment-Experienced
Treatment Regimen
A structured plan of treatment, usually with drugs, that is
implemented to improve or maintain health.
Trial Design
The structure of a clinical study or trial. Examples include open-label
or double-blind, comparative or observational.
Triglycerides
Fat-like substances that help transfer energy from food into cells.
Triglyceride levels that are too high increase the risk of heart disease
and have been associated with diabetes and pancreatitis. Elevated
triglyceride levels are a potential side effect of some PIs.
T
Triple-Class Experienced
A term used to describe an HIV-infected patient who has been
treated with drugs from each of the following three anti-HIV drug
classes: nucleotide/nucleoside reverse transcriptase inhibitors; non-
nucleoside reverse transcriptase inhibitors; and protease inhibitors.
Tropism
See: Viral Tropism
HIV/AIDS Glossary 135