Page 100 - 78 glossary of hivaids-related terms_opt

Open-Label Trial
A clinical trial in which both the researchers and the participants
know who is getting which drug or vaccine.
See Also: Double-Blind Study

Opportunistic Infection (OI)
An illness caused by any one of various organisms that occur in
people with weakened immune systems, including people with
HIV/AIDS. OIs that are common in people with AIDS include
Pneumocystis jiroveci pneumonia (PCP); cryptosporidiosis;
histoplasmosis; toxoplasmosis; other parasitic, viral, and fungal
infections; and some types of cancers.

Optimized Background Therapy (OBT)
The anti-HIV drugs in a treatment regimen that are chosen for an
individual on the basis of resistance testing and treatment history. In
clinical trials, patients often receive either the drug being tested or a
placebo (sugar pill for comparison) in addition to OBT, so that they
do not receive monotherapy or no treatment.

Oral Hairy Leukoplakia (OHL)
O
A white-colored, hairy, or ribbed patch that appears on the side of
the tongue and inside the cheeks. It develops mainly in people with
weakened immune systems, including people with HIV. It is caused
by Epstein-Barr virus (EBV), a member of the herpesvirus family.
See Also: Epstein-Barr Virus (EBV)

Osteonecrosis
Also referred to as avascular necrosis. A medical condition in which
bone tissue dies. Osteonecrosis affects some people with HIV, but
it is unclear if it develops as a complication of HIV infection or as a
side effect of anti-HIV drugs.
See Also: Avascular Necrosis (AVN)

98 HIV/AIDS Glossary