Page 98 - 78 glossary of hivaids-related terms_opt

a normal nucleoside, reproduction of the virus’s genetic material is
halted. Also called nucleoside analogues or nukes.
See Also: Nucleoside
Reverse Transcriptase (RT)

Nucleoside-Associated Resistance Mutation (NAM)
A viral mutation that increases HIV resistance to treatment by
NRTI drugs.
See Also: Thymidine Analogue Mutation (TAM)

Nucleotide
A building block of DNA or RNA, the chemical structures that
store genetic information.
See Also: Deoxyribonucleic Acid (DNA)
Ribonucleic Acid (RNA)

Nucleotide Analogue Reverse Transcriptase Inhibitor (NtRTI)
A class of anti-HIV drug. Nucleotide analogues are faulty versions
of the building blocks necessary for HIV reproduction. When HIV’s
reverse transcriptase enzyme uses a nucleotide analogue instead
N
of a normal nucleotide, reproduction of the virus’s genetic material
is halted. Although technically different from nucleoside analogues,
nucleotide analogues work in the same way. Also called nucleotide
analogues or nukes.
See Also: Nucleotide
Reverse Transcriptase (RT)

Nucleus
The part of a cell that contains the organism’s genetic information.

Nuke
Slang term for nucleoside/nucleotide reverse transcriptase
inhibitors (NRTIs).
See Also: Nucleoside Analogue Reverse Transcriptase Inhibitor (NRTI)
Nucleotide Analogue Reverse Transcriptase Inhibitor (NtRTI)

96 HIV/AIDS Glossary