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308  Oesophageal Atresia

                                                               ter and life threatening and require early intervention. Generally, gastro-
                                                               oesophageal reflux is addressed first. Occasionally, infants cannot be fed
                                                               at all without immediately refluxing and aspirating, and may be at risk
                                                               of sudden infant death syndrome (SIDS).
                                                                 Other  postoperative  complications  include  anastomotic  stricture;
                                                               gastro-oesophageal  reflux;  long-term  Barrett’s  oesophagus  due  to
                                                               chronic reflux; and chylothorax.
                                                                 A well-recognised but uncommon pitfall in the operative management
                                                               of OA, tracheo-oesophageal fistula occurs in the event of a carinal fistula
          Circular Myotomy through the neck  Intrathoracic Circular Myotomy   with tracheal communication into the fork of the carina. In this situation,
                                   through the thoracotomy wound  the relative position of the right main bronchus and distal oesophagus
                                                               just below the fistula is reversed. The surgeon should always confirm
        Figure 48.5: Circular myotomy.                         that a structure isolated as the distal oesophagus is correctly identified by
                                                               atraumatic occlusion and confirmation that the right lung still ventilates
                                                               before dividing the structure.
                                                                                   Conclusion
                                                               In the Western world, current expectations of survival are that all patients
                                                               with oesophageal atresia will survive unless there are major congenital

                                                               malformations affecting other systems. There is no place for technical
                                                               risk or error to compromise survival. In Africa, however, limiting fac-
                                                               tors are delayed diagnosis and restricted access to a neonatal intensive
                                                               care unit (NICU). Shortages of medical and nursing personnel demand
                                                               techniques be selected that limit the NICU requirement, in-hospital stay,
                                                               and complications. The potential to rescue patients with surgical compli-
                                                               cations is probably not as good as it is in First World centres.
                                                                           Evidence-Based Research
                                                               Table 48.1 presents a review of a 10-year personal experience with OA
                                                               and TOF.
                                                               Table 48.1: Evidence-based research.
        Figure 48.6: Flap technique: (1) the closed upper pouch; (2) the upper pouch is
        open and its lateral wall reaches the lower segment of the oesophagus; (3) the   Title  Oesophageal atresia and tracheo-oesophageal fistula: review
        elongated upper pouch is anastomosed to the lower segment.          of a 10-year personal experience.
                                                                 Authors    Adebo OA
                                                                 Institution  Department of Surgery, University College Hospital and
        integrity of the anastomosis. A drain does no harm and can be removed in   College of Medicine, University of Ibadan
        2 or 3 days if one has confidence in the anastomosis. In cases anastomosed
        under tension, a para-anastomotic drain is retained for a week, and feeds   Reference   West Afr J Med 1990; 9(3):164–169
        are delayed until a contrast swallow confirms an intact oesophagus.  Problem  Outcomes of TOF and OA repair in the African setting is poor.
           Gastrostomies  are  essentially  used  only  for  pure  oesophagael   Intervention  This study seeks predictors to improve outcome.
        atresia cases. The rest are fed via a transanastamotic tube initially, and   Comparison/  Eleven neonates with oesophageal atresia and distal fistula
        subsequently are fed orally.                             control    were managed between July 1977 and January 1987. The
           Minimally  invasive  endoscopic  surgery  has  become  the  vogue  in   (quality of   male-to-female ratio was 1.2:1. The patients were aged
                                                                            between 1 to 14 days (median of 7 days) and weighed 1.85
        paediatric  surgery,  and  has  excellent  application  for  a  considerable   evidence)  to 3.10 kg (mean of 2.6 kg) at presentation. Associated
        range of procedures. Whether this is true for thoracoscopic repair of   anomalies were present in 5, pneumonia in 4, and uraemia
        OA since the first report in 1999 is debatable. The foremost and most   (mean serum urea of 88 mg%) in all patients. A primary
                                                                            repair and simultaneous gastrostomy (omitted in one) were
        enthusiastic endoscopic surgeons promote this procedure and claim that   performed for all cases. There were 5 operative deaths.
        their results and complication rates are at least comparable with open   Fifteen postoperative complications occurred in 10 patients,
        operative  procedures.  The  technique  may  be  used  if  equipment  and   including septicaemia in 3, wound infection in 3, anastomotic
                                                                            leak in 1, and tracheal mucous plug in 1. Statistical analysis
        expertise are available.                                            indicated no difference between survivors and nonsurvivors
                   Postoperative Complications                              on the basis of age, weight, degree of uraemia, or presence of
                                                                            pneumonia. One of the 6 survivors (now 5 years after surgery)
        An anastomotic leak may have dire consequences if a major intrapleural   required bouginage after 26 months and has remained
                                                                            asymptomatic; the other 5 are well and without symptoms 3 to
        disruption occurs. Anastomotic leaks should be uncommon and, if extra-
                                                                            11 months postoperative.
        pleural and contained, can be treated expectantly by maintaining parenter-
                                                                 Outcome/   High mortality and morbidity for this neonatal condition.
        al nutrition and drainage until the leak seals and heals. A major intrapleural
                                                                 effect
        disruption  can  be  life  threatening  and  warrants  early  re-exploration.  If
        total disruption occurs, the oesophagus may have to be abandoned and the   Historical   The most significant determinants of survival are the
        upper pouch exteriorised as a cervical oesophagostomy.   significance/  effectiveness of pre- and postoperative managements of
                                                                 comments   patients.
           A recurrent tracheo-oesophageal fistula requires operative interven-
        tion, closure, and tissue interposition, although endoscopic injection of
        glue has been described.
           Another  complication  is  stridor  and  cyanotic  episodes  related  to
        tracheomalacia  and  a  collapsing  upper  airway.  The  combination  of
        gastro-oesophageal reflux and tracheomalacia may be particularly sinis-
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