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CHAPTER 9

                         Vascular Access in Children



                                                      James O. Adeniran
                                                         Hugo A. Heij






                             Introduction                        Table 9.1: Indications for peripheral vascular access.
          Every child presenting to the paediatric surgeon will require vascular   Indications      Uses
          access  at  one  time  or  another  during  the  management  of  the  child’s
          surgical condition. Vascular access becomes critical in patients brought   Venous blood sampling  For various diagnostic tests
          to the hospital as emergencies because many of them may have been   Resuscitation   Fluids, blood and blood products in:
          on treatment in private hospitals for some time, and the obvious veins         Intestinal obstruction
          have been used already. This common task may be even more daunting             Peritonitis
          with factors such as restlessness due to the clinical pathology, shock,        Trauma
          unavailability  of  appropriate  catheters,  obese  patients,  and  children   Preoperative work-up
                              1
          with multiple limb injuries.  It is therefore important for the paediatric
          surgeon to be familiar with how to gain access to the vascular tree as   Administration of other products   Drugs during resuscitation
          and when necessary.                                                            Drugs during anaesthesia
            The first part of this chapter considers peripheral vascular access,         Correction of anaemia/coagulation defects
          and  the  second  part  considers  central  vascular  access.  Indications,    Parenteral nutrition
          techniques  of  catheter  insertion,  complications  and  management  of       Cytotoxic drugs
          these complications, and the cost-benefit aspect in the African setting
          are discussed.                                          Use as central venous access
                     Peripheral Vascular Access
          Indications for Africa                                 the  gastrointestinal  tract  may  need  digital  substraction  angiography
          Virtually all patients presenting to a paediatric surgeon need blood tests   (DSA) for diagnosis and management. Many advanced liver and renal
          for  diagnosing  their  ailments,  assessing  their  fitness  for  anaesthesia,   tumours can now be embolised by using the arterial route with excel-
          and use in postoperative management. Accurate figures for Africa are   lent palliation.
          not known, but in the United States an estimated more than 200 mil-  Physiology
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          lion peripheral catheters are placed annually.  Vascular access is one of   The French physiologist Jean Marie Poiseuille  in 1839 defined resis-
                                          2
          the new tools that enables the neonatologist and paediatric surgeon to   tance through a vessel as:
          provide ongoing therapy for very ill babies, at the same time allowing   Resistance = 8 (viscosity) (catheter length) / πr 4
                                           3
          invasive monitoring of the clinical condition.  Many patients present to
          the paediatric emergency room with intestinal obstruction as neonates   Resistance  through  the  catheter  decreases  as  the  length  of  the
          with anorectal malformations, Hirschsprung’s disease, or bowel atre-  catheter  decreases  and  the  radius  r  increases.  Maximum  flow  is
          sias.  Older patients present with peritonitis, usually due to typhoid or   therefore best when the catheter is short and wide.
             4
                          5
          appendix perforation.  Some patients also present with multiple trauma,   Sites of Peripheral Vascular Access
          and others may present with sickle cell disease in crises. These patients   Venepuncture
          need urgent vascular access for administration of fluids, blood prod-  Umbilical vein
          ucts, drugs, and nutritional formulas.
                                     3
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                                                                 The umbilical vein may remain patent for up two weeks.  It is easily
          Venous Access                                          cannulated in neonates and is used extensively in third-world countries
          Venous  access  is  needed  for  administration  of  drugs  during  resusci-  for  venous  blood  sampling,  infusion  of  crystalloids  and  colloids,
          tation,  induction  and  maintenance  of  anaesthesia,  during  cytotoxic   administration of drugs, and exchange blood transfusion. The technique
          therapy, and in haemodialysis. Stem-cell harvest for research and bone   is described below. Portal vein thrombosis can follow prolonged use;
          marrow transplantation in cases of leukaemias also need venous access.   therefore,  a  peripheral  vein  should  be  secured  as  soon  as  possible.
          Nutritional support can be given to many patients through peripherally   Platelets should not be infused through the umbilical vein.
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          inserted central catheters. Other indications and uses for venous access   Upper limb
          are shown in Table 9.1.                                The upper limb is the preferred site for cannulation in children. Because
          Aterial Access                                         the dorsal venous arch starts from the dorsum of the wrist, this site is
          Arterial access is used much less in developing countries, not because   most commonly attempted first in most children. Two or three veins
          the  indications  are  lacking,  but  because  the  necessary  equipment  is   may be found at the radial and ulna borders. The origin of the cephalic
          not available. Arterial sampling for O  estimation and cardiovascular   vein may be seen over the snuff box in older children. The cephalic and
                                      2
          monitoring in very ill children, especially those who need ventilation,   basilic veins and one or two veins crossing them may be visible at the
          needs arterial access. Various radiological procedures for diagnosis and   cubital fossa.
          treatment  are  becoming  popular  in  children.  Children  bleeding  from
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