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50  Vascular Access in Children

           Care should be taken not to injure the corresponding artery, especially   Table 9.2: Advantages and disadvantages of different routes for central
        during cutdowns. Once the vein is exposed, the artery should be clearly   venous access.
        palpated before any vessel is ligated. Complications from intraosseous
        infusions  are  rare,  but  skin  necrosis,  compartment  syndromes,  and   Access  Advantages  Disadvantages
        osteomyelitis can occur.                                Arm veins    Simple to access, veins   Failure to achieve central
                      Central Venous Access                                  visible, and palpable   position
                                                                             Not close to vital organs   High incidence of
        This section discusses the purposes of central venous access (CVA), the
                                                                             Comfortable for patient  thrombosis
        techniques and devices tailored to the purposes, and the complications
                                                                                                Low maximum infusion
        (both short- and long-term). For long-term central venous access, an                    rates
        operating theatre and general anaesthesia with fluoroscopy are ideal,
                                                                Internal jugular  Simple to insert   Uncomfortable for patient
        and will give the best results. The cost-benefit aspect of CVA in the
                                                                             Direct route to central veins  High rate of long-term
        African setting is addressed in the final paragraph.                                    complications
                                                                             High flow-rate
        Incidence/Prevalence in the African Setting                          Low risk of thrombosis  Tunneling to chest wall
        Percutaneously  placed  short-term  central  venous  catheters  (CVCs)   Low risk of pneumothorax  more difficult
        have been the primary means of central venous access in critically ill
              13
        children.  Central venous access for administration of drugs or blood   Subclavian/axillary  Less patient discomfort   Curved incision route
        products  can  be  required  urgently  in  patients  with  severe  trauma  or   Lower risk of long-term   Difficult to access
                                                                             complications
        other life-threatening conditions. A chronic need for CVA will arise in                 Higher rate of pneumo/
        patients with oncological or intestinal conditions and for total parental               haemothorax
        nutrition.  About 5 million CVCs are inserted in the United States annu-  Femoral  High flow rate  Higher rate of infection/
               13
                                                                                                thrombosis
           2
        ally.  The role of the paediatric surgeon in CVA is to offer service to   Good for dialysis
        paediatric doctor colleagues, and the need for CVA will depend on the   Easy insertion  More discomfort for patient
        type of paediatric (surgical) practice.                                                 Difficult in obese patients
           The  main  patient  categories  are  oncology,  congenital  intestinal
        malformations, and short bowel syndrome, with lesser demands from
        haematology (sick cell disease) and orthopedics (intravenous antibiotics
        for septic arthritis and osteomyelitis). Devices and facilities for CVA are
        expensive, so the applicability also depends on financial considerations.
        Applications and Indications
        The indications of central venous access include:
         • rapid infusion of intravenous fluids and blood products;
         • frequent blood sampling/blood transfusions;
         • administration of substances that are likely to damage peripheral
          veins, such as cytotoxics or hyperosmolar parenteral nutrition (PN);
         • long-term administration of drugs (antibiotics) or blood products,
          obviating the need for repeated venepunctures in children;
         • central venous pressure and haemodynamic monitoring of acutely
          ill patients; and
         • haemodialysis.
        Clinical Considerations
        Need for emergency central venous access
        In patients with life-threatening conditions, the need for CVA is obvious   Courtesy: Bard Access Systems.
                                                               Figure 9.4: A double-lumen Hickman catheter.
        at presentation. Although large-bore peripheral cannulas may be used
        for initial access in the emergency room, CVA will be required as soon
        as the patient is admitted to the intensive care unit (ICU). Four routes   Types of Catheters
        are available for transcutaneous insertion of a central venous catheter:   A typical catheter for long-term use (such as seen in Figure 9.4) has the
        1. cephalic or basilic veins in the arm;                following essential features:
                                                                • Is manufactured from soft silicon rubber or polyvinyl chloride
        2. internal jugular vein;
                                                                 (PVC).
        3. subclavia vein; or
                                                                • Is chemically inert, nonthrombogenic, flexible, and radio-opaque.
        4. femoral vein.
           The advantages and disadvantages of these routes are summarised   • May have single-, dual-, or triple-lumen, which allows simultane-
        in Table 9.2.                                            ous infusion or infusion of incompatible solutions.
        Long-term Use of Central Venous Access                  • Has a Dacron cuff (e.g., SureCuff ), which has a matrix that
                                                                                         ®
        Long-term  CVA  is  mainly  required  for  administration  of  cytotoxics   expands after insertion and into which subcutaneous fibrous tissue
        and/or parenteral nutrition. The techniques of insertion and the devices   grows for good anchorage.
        are different from those used in emergency CVA.
                                                                          ®
                                                                • Is a VitaCuff , which incorporates an antimicrobial collagen sponge
                                                                 designed to prevent infection.
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