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Vascular Access in Children  49
          Venous Cutdown                                         theless, foreign bodies. Catheters should therefore be retained only for as
          A cutdown may be necessary to establish a rapid vascular access, for   long as necessary. Feeding and drugs should be changed to the oral route
          example, when all visible superficial veins may have been used or the   as soon as possible. After 2–3 days, signs of inflammation may appear
          patient comes in shock. The long saphenous vein, either near the ankle   at the site of cannulation. These include pain, redness, and swelling. If
          or at the groin, the femoral vein at the groin, and the basilic vein at the   the redness appears other than along the site of cannulation, cellulitis
          elbow or the cephalic vein at the delto-pectoral grove are all suitable   is setting in, and the site of cannulation will need to be changed. If the
          sites. The area around the chosen vein is cleaned and draped aseptically,   catheter  is  being  used  for  parenteral  nutrition,  intravenous  antibiotics
          then infiltrated with a suitable local anaesthetic. A transverse incision is   may be given in an attempt to salvage the line. If the catheter is planned
          made only in the skin over the vein. A haemostat is then used to widely   for long-time use, it may be advisable to give regular antibiotics through
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          open  the  subcutaneous  tissues. The  vein  is  usually  then  visible. The   the  vein  from  the  beginning.   The  presence  of  infection  elsewhere,
          distal end of the vein is ligated. A small needle is passed transversely   prolonged hospital stay, immunosuppression, and poor catheter care all
          across the vein, and the part of the vein superficial to the needle is tran-  contribute to catheter-related sepsis.
          sected. A suitable catheter is then inserted and anchored with stitches.   Thrombosis/thrombophlebitis
          The  transverse  skin  incision  is  closed  with  one  or  two  stitches. The   Thrombosis  can  occur  in  a  catheter,  and  the  thrombus  can  dislodge
          catheter is anchored to skin with both stitches and plaster.
                                                                 to distant parts with grave consequences to the patient. Early signs of
          Intraosseous Infusion                                  thrombosis  are  inadequate  flow  in  the  infusion  fluid  and  extravasa-
          The bone marrow space is a rich, noncollapsible venous network.  tion. Use of silicone catheters, parenteral nutrition, and diabetes may
             Intraosseous infusion is a quick method of resuscitating children in   predispose the patient to thrombosis. Aortic thrombosis can complicate
          shock when immediate intravenous access fails. Crystalloids, colloids,   umbilical artery cannulation, which may lead to leg or bowel gangrene.
          drugs  (including  anaesthetic  drugs),  and  blood  can  be  given  rapidly   If persistent blanching of skin of the leg occurs, the catheter may need to
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          through this route.  The flat, anteromedial, subcutaneous, upper aspect   be removed. Regular flushing with normal saline, heparin, or urokinase
          of the tibia 1–3 cm below the tibia tuberosity is usually used (Figure   may  serve  as  a  preventive. After  the  catheter  has  been  removed,  the
          9.3). Other sites that could be used are:              vein may become a painful, fibrotic, noncompressible “cord”. This is
           • the midline of the distal femur 3 cm proximal to the femoral         thrombophlebitis. Only painkillers are necessary, as the condition usu-
            condyles;                                            ally settles with time.
           • distal tibia proximal to the medial malleolus;      Extravasation/skin necrosis
                                                                 When a new catheter is inserted in a vein, sterile water or saline should
           • anterior superior iliac spine;
                                                                 be injected first and must be seen to flow freely before the injection of
           • lateral malleolus; or                               drugs. If this is not done, drugs containing calcium, bicarbonate, or thio-
                                                                 pentone, and drugs for chemotherapy can extravasate into subcutaneous
           • proximal humerus distal to deltoid insertion.
                                                                 tissues, causing necrosis. The dorsum of the hand and foot are common
                                                                 sites. If a toxic drug is given accidentally, application of ice packs to
                                                                 the area, subcutaneous irrigation with water or saline, and injection of
                                                                 hyaluronidase or steroid may reduce the amount of tissue damage.  If
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                                                                 frank skin necrosis occurs, debridement, sometimes with delayed skin
                                                                 grafting, may be necessary.
                                                                 Cannula dislodgement/fracture/embolisation
                                                                 Catheters  need  to  be  anchored  properly  with  plaster,  and  cutdowns
                                                                 should be secured with stitches. Brisk bleeding can occur when an arte-
                                                                 rial catheter inadvertently dislodges. Pressure for a couple of minutes
                                                                 will  usually  stop  the  bleeding.  Appropriate  splints  are  necessary  in
                                                                 restless children. If frequent intravenous injections are necessary in a
                                                                 restless or shocked patient, or if a patient is receiving rapid intravenous
                                                                 infusions, a second line should be considered. Fracture of a cannula with
                                                                 embolism at distant sites has been reported.
                                                                 Complications
          Figure 9.3: Technique of intraosseous infusion.        Complications of peripheral cannulation include:

                                                                  • haemorrhage/failed cannulation;
             The chosen site is cleaned and draped, and a little local anaesthetic
          is  given. A  Jamshidi  needle  (which  has  a  trochar),  or  bone  marrow   • air embolus during catheter insertion, tube change, or tube removal;
          needle, or any size 13–18 butterfly needle can be used. The needle is   • infection/cellulitis;
          introduced perpendicular to the skin, then angled away from the growth   • thrombosis/thrombophlebitis;
          plate until a “give” is felt. The trochar is then removed. Blood should be
          aspirated to confirm that the needle is in the marrow. The infusion fluid   • extravasation/ skin necrosis;
          can then be connected. Sterile gauze and plaster are used to secure the   • cannula dislodgement/fracture/embolisation;
          needle. The intraosseous route is for emergency only, and should not be
          used for more than 2–3 hours. As soon as possible, it should be replaced   • injury to surrounding structures (artery, nerve, solid organs);
          by a suitable intravenous site.                         • compartment syndrome/osteomyelitis; and
          Complications of Peripheral Vascular Access
                                                                  • ugly scars from subcutaneous extravasation, when debridement and
          Infection/cellulitis                                     skin grafting have been done.
          Although our bodies do not normally react to catheters, they are, never-
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