Page 7 - Noninvasive Diagnostic Techniques for the Detection of Skin Cancers

Contents
Background ................................................................................................................................... 1
Current and Emerging Modalities of Assessment and Diagnosis ............................................. 1
Statement of Work/Objectives .................................................................................................. 2
Guiding Questions ......................................................................................................................... 3
Analytic Framework ................................................................................................................. 4
Methods .......................................................................................................................................... 6
Systematic Searches of the Published Literature ...................................................................... 6
Searches of the Grey Literature ................................................................................................ 6
Interviews With Key Informants .............................................................................................. 7
Data Collection ......................................................................................................................... 7
Data Organization and Presentation .......................................................................................... 8
Findings .......................................................................................................................................... 9
Devices in General Clinical Use ............................................................................................. 13
Photography .......................................................................................................................13
Available Literature .................................................................................................... 13
Description of Technique ............................................................................................ 13
Variations of Technique .............................................................................................. 15
Clinical Context of Use ............................................................................................... 15
FDA Status .................................................................................................................. 16
Summary ..................................................................................................................... 16
Dermoscopy .......................................................................................................................16
Available Literature .................................................................................................... 16
Description of Technique ............................................................................................ 17
Variations of Technique .............................................................................................. 19
Clinical Context of Use ............................................................................................... 19
FDA Status .................................................................................................................. 21
Summary ..................................................................................................................... 21
Devices in Limited Clinical Use ..............................................................................................22
Confocal Microscopy .........................................................................................................22
Available Literature .................................................................................................... 22
Description of Technique ............................................................................................ 22
Variations of Technique .............................................................................................. 23
FDA Status .................................................................................................................. 24
Summary ..................................................................................................................... 24
Ultrasound/Laser Doppler ..................................................................................................24
Available Literature .................................................................................................... 24
Description of Technique ............................................................................................ 24
Variations of Technique .............................................................................................. 25
FDA Status .................................................................................................................. 26
Summary ..................................................................................................................... 26
Photodynamic Diagnosis ...................................................................................................26
Available Literature .................................................................................................... 26
Description of Technique ............................................................................................ 27
Variations of Technique .............................................................................................. 27
FDA Status .................................................................................................................. 27

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