Page 94 - Cardiac testing for coronary artery disease in potential kidney transplant recipients

Table 1. Description of index tests (Continued)

sured via gas ex-
change data

DSF Used to detect coro- Non-invasive Not commonly Dichotomous (i.e. None
nary artery calcifi- Non exercise used presence or absence
cation. Digital sub- Radiation dose of calcification)
traction
improves resolution
of conventional flu-
oroscopic methods

Exercise radionu- Technique Not commonly Dichotomous (i.e. None. However,
cleotide ventricu- for a combined as- used stress test positive or whether a stress test
lography sessment of exercise Radiation dose stress test negative) is interpreted as pos-
capacityandaneval- itive or negative de-
uation of ventricu- pends largely on ob-
lar size and perfor- server interpretation
mance
Reference standard

Coronary angiog- Coronary catheteri- Gold standard for High cost Dichotomous (i.e. Yes (i.e. ≥ 50%
raphy sation is an invasive detecting CAD. Lack of sensitivity to presence or absence stenosis or ≥ 70%
procedure to access Enables diagnosis of intramural coronary of significant CAD) stenosis).
the coronary cir- precise location and atherosclerosis We managed the is-
culation and blood severity of each le- Risk of complica- sue of different cut
filled chambers of sion tions points by involving
the heart using a In- Intravenous an analysis which
catheter. It can be tervention (PTCA) contrast media may included:
performed for both possible during pro- worsen kidney func- • All studies
diagnostic and in- cedure tion regardless of
terventional (treat- Little information threshold of CAD
ment) purposes. It on function on coronary
assessesthe diameter Radiation dose angiography (these
of Results subject to will include both
coronary artery lu- interpretation studies which have
mens, heart cham- and reader bias, al- ≥ 50% stenosis and
ber size and heart though toalesserex- ≥ 70% stenosis
muscle contraction tent than functional • Only studies
performance tests which had ≥ 70%
stenosis threshold

CAD: coronary artery disease; CIMT: carotid intimal medial thickness; CT: computed tomography; ECG: electrocardiograph; MPS:
myocardial perfusion scintigraphy; MRI: magnetic resonance imaging; PTAC: percutaneous transluminal coronary angioplasty

Cardiac testing for coronary artery disease in potential kidney transplant recipients (Review) 92
Copyright © 2011 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.