Page 98 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer

Table 7. Eligibility criteria for enrollment in protocols with palliative intent in chronological order of starting enrollment year (continued)
Center, Country Term Age PSA Gleason score # biopsy Imaging Stage Behavioral indication (other than
[Pubmed ID] used (yr) (ng/mL) cores /% patients’ choice or preference)
Enrollment cores
years
Taichung No – – – – – T1a –
Veterans treatment
Hospital,
Taiwan 143
[12854876]

1983-1996
SPCG-4, Finland, WW <75 <50 If diagnosed with an – Bone scan T0d, T1 or –
Sweden, and extended biopsy negative T2; T1c
Iceland 144 protocol, <25% of the (after 1994)
[12226148] tumor Gleason grade
4 and <5% grade 5
1989-1999
Erasmus Univ. No 50- ≤15 150 <8 150 – Bone scan T1c or T2 150 No treatment decision was made by the
Hospital, treatment 75 a151 and chest urologist in discussion with the patient
Netherlands 145 /AS 150 x-ray and his family, with respect to patient
[7544841] negative age, general health, clinical stage and
patient preference. 145 All patients had
≤1990; 1993- estimated survival >1 yr.
2006 150
Royal Marsden WW – Any ≤7 – – any T stage, Unsuitable for RP typically because
Hospital, UK 112 N0/X, advanced age or comorbidities.
[15839912] M0/X

1993-2002
PIVOT, US 146 WW ≤75 ≤50 Any – Bone scan T1- –
[18783735] negative T2/Nx/M0

1994-2002
Watchful Waiting WW <85 <50 <8 – – – > 3-yr life expectancy, no history of any
Study, US 147 type of malignancy within the past 5 yr
[14501381] with the exception of non-melanoma
skin cancer
1998-2003

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