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Figure 3. Years covered and databases utilized by studies considered eligible for Key Question 1
                                 Mebane, 1990 [2258952]
                                 Hankey, 1999 [10379964]
                                  Chu, 2003 [12627516]
                                Severson, 1995 [7707440]
                                  Merrill, 1999 [10522656]
                                 Brawley, 1997 [9351560]
                                  Hayat, 2007 [17227898]
                                  Perrotti, 1998 [9720554]
                                  Merrill, 2002 [11790678]
                                  Merrill, 1997 [9229202]
                               Stephenson, 2002 [12109343]
                                Escobedo, 2004 [15542264]
                                 Demers, 1994 [8203988]
                                  Farkas, 1998 [9730458]
                                 Schwartz, 1996 [8826949]
                                  Clegg, 2002 [12381706]
                                  Merrill, 2000 [10792091]
                                 Demers, 2001 [11745285]
                                 Dennis, 2000 [10679753]
                                  Smart, 1997 [9351557]
                                  Hsing, 2000 [10585584]
                                McDavid, 2004 [15192905]
                             Barnholtz-Sloan, 2003 [14575366]
                                  Jani, 2008 [18845997]
                                Newcomer, 1997 [9302136]
                                  Clegg, 2002 [12230422]
                                  Collin, 2008 [18424233]
                                 Devesa, 1995 [7707404]
                                 Mariotto, 2006 [16572414]
                                  Danley, 1995 [8580296]
                                 Sarma, 2002 [11828352]
                                Schwartz, 1999 [10197854]
                                 Gilliland, 2001 [11176484]
                                 Gilliland, 1996 [8722215]
                                  Merrill, 1996 [8931614]
                                  Lu-Yao, 1994 [7905093]
                                  Jani, 2007 [17505529]
                                  Harlan, 1995 [7799048]
                               Stephenson, 1996 [8608513]
                                  Mettlin, 1994 [8062197]
                                  Mettlin, 1996 [8640686]
                                 Potosky, 1995 [7530782]
                                 Welch, 2009 [19720969]
                                 Sheikh, 2002 [11880074]
                                 Klabunde, 1998 [9749657]
                                 Godley, 2003 [14625261]
                                  Mettlin, 1995 [8625214]
                                  Miller, 2006 [16912266]
                                Abdollah, 2011 [20965646]
                                  Merrill, 2000 [10647666]
                                  Shao, 2009 [19713548]
                               Cooperberg, 2003 [14610406]
                               Cooperberg, 2003 [12837834]
                                 Kindrick, 1998 [9817332]
                               Cooperberg, 2002 [12131295]
                               Cooperberg, 2004 [15169800]
                                 Harlan, 2003 [14532780]
                                 Stewart, 2004 [15179359]
                               Cooperberg, 2007 [17644125]
                               Cooperberg, 2008 [18369637]
                                   Zhu, 2009 [19505907]
                               Cooperberg, 2010 [20124165]
                                 Warren, 2008 [18544740]
                                 Zeliadt, 2004 [15596192]
                                  Mettlin, 1998 [9781963]
                                 Mettlin, 1999 [10547563]
                                 Gross, 2008 [18181101]
                               Underwood, 2004 [15017208]
                                 Paltoo, 2004 [15219802]
                               Underwood, 2005 [15612083]
                                Polednak, 2002 [12477140]
                                 Welch, 2007 [17848671]
                                Carpenter, 2010 [20333462]
                                  Shah, 2008 [17997437]
                                  White, 2011 [21351084]
                                 Greene, 2005 [16194711]
                                 Mullins, 2010 [20163844]
                                Hamilton, 2011 [20735387]
                                 Kohler, 2011 [21454908]
                                              1970        1980        1990        2000        2010

                                                                  Years covered
                                                                  SEER
                                                                  SEER component registries
                                                                  SEER-Medicare
                                                                  CaPSURE
                                                                  NCDB
                                                                  Other

               Horizontal lines indicate the years covered by each primary study considered for Key Question 1. Different line patterns indicate
               the different databases utilized by each study. Studies are listed by the first year covered, then by database used, then by year of
               publication and are presented using the format: first author, year of publication [MEDLINE unique identifier]. Though data from
               earlier years were available, we analyzed only data from 1980 onward. Studies using SEER along with other information sources
               have been grouped in the “SEER” category for simplicity.
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