Page 81 - 16Neonatal Jaundice_compressed

Neonatal jaundice

Study details Study Risk factor
population Family history of GA < 38 weeks or Sex Race Exclusive Early clinical Severity of Bruising or cephalo- Delivery Maternal
jaundice early gestation breastfeeding jaundice jaundice haematoma characteristics characteristics
Gale et al. Term singleton Previous sibling with For 37 weeks: OR 4.5 Male Vacuum Maternal age
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(1990) babies (GA jaundice: OR 2.3 (3.2–6.3) sex: extraction: OR 3.0 > 35 years: OR 1.7
[EL II] ≥ 37 weeks) (1.9–2.8) For 38 weeks: OR 2.1 OR 1.4 (2.1–4.4) (1.3–2.3)
(1.6–2.8) (1.2– Primipara: OR 2.7
1.7) (2.1–3.5)
40 weeks as reference
Khoury et al. Both term and Risk of recurrence in
(1988) preterm babies siblings depending on
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[EL II] degree of jaundice (in
micromol/litre):
Mild (serum bilirubin
≤ 205):
OR 2.7 (1.8–4.1)
Moderate (serum
bilirubin 205–257):
OR 4.1 (1.5–10.8)
Severe (serum
bilirubin ≥ 257):
OR 12.5 (2.3–65.3)
Maisels et al. Both term and For 35 to OR 10.75 (2.37–
(2009) preterm babies 36 6/7 weeks: 48.82)
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[EL II] OR 20.79 (2.34–
184.74)
For 37 to
37 6/7 weeks:
OR 14.86 (1.91–
115.38)
40 to 40 6/7 weeks as
reference
BW = birthweight; CI = confidence interval; EL = evidence level; GA = gestational age; NS = not statistically significant; OR = odds ratio; RR = risk ratio.
Results from multivariate analysis are reported as an OR with a 95% CI.

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