Page 80 - 16Neonatal Jaundice_compressed
P. 80

Neonatal jaundice





                     Study details  Study                                                   Risk factor
                              population   Family history of   GA < 38 weeks or  Sex   Race   Exclusive   Early clinical  Severity of  Bruising or cephalo- Delivery   Maternal
                                         jaundice      early gestation           breastfeeding   jaundice   jaundice   haematoma   characteristics   characteristics
                     Gale et al.   Term singleton   Previous sibling with  For 37 weeks: OR 4.5  Male                         Vacuum      Maternal age
                        15
                     (1990)    babies (GA   jaundice: OR 2.3   (3.2–6.3)   sex:                                               extraction: OR 3.0  > 35 years: OR 1.7
                     [EL II]   ≥ 37 weeks)   (1.9–2.8)   For 38 weeks: OR 2.1   OR 1.4                                        (2.1–4.4)   (1.3–2.3)
                                                       (1.6–2.8)     (1.2–                                                                Primipara: OR 2.7
                                                                     1.7)                                                                 (2.1–3.5)
                                                       40 weeks as reference
                     Khoury et al.   Both term and   Risk of recurrence in
                     (1988)    preterm babies   siblings depending on
                        16
                     [EL II]             degree of jaundice (in
                                         micromol/litre):
                                         Mild (serum bilirubin
                                         ≤ 205):
                                         OR 2.7 (1.8–4.1)
                                         Moderate (serum
                                         bilirubin 205–257):
                                         OR 4.1 (1.5–10.8)
                                         Severe (serum
                                         bilirubin ≥ 257):
                                         OR 12.5 (2.3–65.3)
                     Maisels et al.   Both term and      For 35 to               OR 10.75 (2.37–
                     (2009)    preterm babies          36 6/7 weeks:             48.82)
                        17
                     [EL II]                           OR 20.79 (2.34–
                                                       184.74)
                                                       For 37 to
                                                       37 6/7 weeks:
                                                       OR 14.86 (1.91–
                                                       115.38)
                                                       40 to 40 6/7 weeks as
                                                       reference
                     BW = birthweight; CI = confidence interval; EL = evidence level; GA = gestational age; NS = not statistically significant; OR = odds ratio; RR = risk ratio.
                     Results from multivariate analysis are reported as an OR with a 95% CI.














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