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Diarrhoea and vomiting caused by gastroenteritis in children under 5 years




                        Treat suspected or confirmed shock with a rapid intravenous infusion of 20 ml/kg of 0.9% sodium
                        chloride solution.
                        If a child remains shocked after the first rapid intravenous infusion:
                        •  immediately give another rapid intravenous infusion of 20 ml/kg of 0.9% sodium chloride
                          solution and
                        • consider possible causes of shock other than dehydration.

                        Consider consulting a paediatric intensive care specialist if a child remains shocked after the
                        second rapid intravenous infusion.
                        When symptoms and/or signs of shock resolve after rapid intravenous infusions, start rehydration
                        with intravenous fluid therapy
                        If intravenous fluid therapy is required for rehydration (and the child is not hypernatraemic at
                        presentation):
                        •  use an isotonic solution such as 0.9% sodium chloride, or 0.9% sodium chloride with 5%
                          glucose, for fluid deficit replacement and maintenance
                        •  for those who required initial rapid intravenous fluid boluses for suspected or confirmed
                          shock, add 100 ml/kg for fluid deficit replacement to maintenance fluid requirements, and
                          monitor the clinical response
                        •  for those who were not shocked at presentation, add 50 ml/kg for fluid deficit replacement to
                          maintenance fluid requirements, and monitor the clinical response
                        •  measure plasma sodium, potassium, urea, creatinine and glucose at the outset, monitor
                          regularly, and alter the fluid composition or rate of administration if necessary
                        •  consider providing intravenous potassium supplementation once the plasma potassium level
                          is known.
                        If intravenous fluid therapy is required in a child presenting with hypernatraemic dehydration:
                        •  obtain urgent expert advice on fluid management
                        •  use an isotonic solution such as 0.9% sodium chloride, or 0.9% sodium chloride with 5%
                          glucose, for fluid deficit replacement and maintenance
                        •  replace the fluid deficit slowly – typically over 48 hours
                        •  monitor the plasma sodium frequently, aiming to reduce it at a rate of less than 0.5 mmol/l
                          per hour.
                        Attempt early and gradual introduction of oral rehydration therapy during intravenous fluid therapy.
                        If tolerated, stop intravenous fluids and complete rehydration with oral rehydration therapy.

                        5.5  Fluid management following dehydration
                        After rehydration:

                        •  encourage breastfeeding and other milk feeds
                        •  encourage fluid intake
                        •  in children at increased risk of dehydration recurring, consider giving 5 ml/kg of ORS
                          solution after each large watery stool. These include:
                          –  children younger than 1 year, particularly those younger than 6 months
                          –  infants who were of low birthweight
                          –  children who have passed more than five diarrhoeal stools in the previous 24 hours
                          –  children who have vomited more than twice in the previous 24 hours.
                        Restart oral rehydration therapy if dehydration recurs after rehydration.


                        Chapter 6  Nutritional management
                        During rehydration therapy:
                        •  continue breastfeeding
                        •  do not give solid foods
                        •  in children with red flag symptoms or signs (see Table 4.6), do not give oral fluids other than
                          ORS solution


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