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Summary of recommendations







                           Suspect hypernatraemic dehydration if there are any of the following:
                           •  jittery movements
                           •  increased muscle tone
                           •  hyperreflexia
                           •  convulsions
                           •  drowsiness or coma.
                           4.2  Laboratory investigations for assessing dehydration

                           Do not routinely perform blood biochemical testing.
                           Measure plasma sodium, potassium, urea, creatinine and glucose concentrations if:
                           •  intravenous fluid therapy is required or
                           •  there are symptoms and/or signs that suggest hypernatraemia.
                           Measure  venous  blood  acid–base  status  and  chloride  concentration  if  shock  is  suspected  or
                           confirmed.

                           Chapter 5  Fluid management
                           5.1  Primary prevention of dehydration

                           In children with gastroenteritis but without clinical dehydration:
                           •  continue breastfeeding and other milk feeds
                           •  encourage fluid intake
                           •  discourage the drinking of fruit juices and carbonated drinks, especially in those at increased
                             risk of dehydration
                           •  offer oral rehydration salt (ORS) solution as supplemental fluid to those at increased risk of
                             dehydration.

                            5.2 Treating dehydration
                           Use ORS solution to rehydrate children, including those with hypernatraemia, unless intravenous
                           fluid therapy is indicated.

                           5.3  Optimal composition and administration of oral fluids
                           In children with clinical dehydration, including hypernatraemic dehydration:

                           •  use low-osmolarity ORS solution (240–250 mOsm/l)* for oral rehydration therapy
                           •  give 50 ml/kg for fluid deficit replacement over 4 hours as well as maintenance fluid
                           •  give the ORS solution frequently and in small amounts
                           •  consider supplementation with their usual fluids (including milk feeds or water, but not fruit
                             juices or carbonated drinks) if they refuse to take sufficient quantities of ORS solution and do
                             not have red flag symptoms or signs (see Table 4.6)
                           •  consider giving the ORS solution via a nasogastric tube if they are unable to drink it or if
                             they vomit persistently
                           •  monitor the response to oral rehydration therapy by regular clinical assessment.
                           5.4  Intravenous fluid therapy
                           Use intravenous fluid therapy for clinical dehydration if:

                           •  shock is suspected or confirmed
                           •  a child with red flag symptoms or signs (see Table 4.6) shows clinical evidence of
                             deterioration despite oral rehydration therapy
                           •  a child persistently vomits the ORS solution, given orally or via a nasogastric tube.



                           *  The  BNF  for  Children  (BNFC)  2008  edition  lists  the  following  products  with  this  composition:  Dioralyte®,  Dioralyte®  Relief,
                            Electrolade® and Rapolyte®.


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