Page 72 - 78 glossary of hivaids-related terms_opt

Inoculation
See: Vaccine

INSIGHT
See: International Network for Strategic Initiatives in Global HIV Trials

Institutional Review Board (IRB)
A committee of experts who review and monitor clinical trials to
ensure that they are ethical and that the rights of study participants
are protected. Federal regulations dictate that any institution that
conducts or supports clinical trials must have an IRB.

I Insulin
A hormone produced by the pancreas to regulate blood sugar.
Because of this regulatory activity, insulin plays a role in the
development and control of diabetes mellitus and other conditions
that affect blood sugar levels.
See Also: Diabetes

Insulin Resistance
An abnormal body response to insulin, a hormone that regulates
glucose (sugar) levels. People with insulin resistance have
abnormally high blood levels of insulin, which may lead to heart and
cholesterol problems and obesity. Insulin resistance may occur in
HIV-infected individuals taking certain PIs.

Insulin Sensitivity
The body’s ability to respond to insulin’s signal to take up glucose
from the blood. Normal insulin sensitivity encompasses a wide
range; people who have low insulin sensitivity may also be
considered insulin resistant, which would result in an increase of
insulin secretion.

70 HIV/AIDS Glossary