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Final Report Update 1                                             Drug Effectiveness Review Project



               APPENDIX E. Abstract-only Studies (not included)

               1.  Bayer AJ, Rossor M, Hecker J, Gauthier S, Burns A, Petite H, et al. Donepezil improves functional
                    activity in patients with Alzheimer's Disease. XXIst Collegium Internationale Neuro-
                    psychopharmacologicum, Glasgow, Scotland. 12th-16th July, 1998. 1998(ABSTRACT REF:
                    PW11015).

               2.  Cummings J, Anand R, Koumaras B, Hartman R. Rivastigmine provides behavioral benefits to
                    Alzheimer's disease patients residing in a nursing home: findings from a 26-week trial. Neurology
                    2000;54(Suppl 3):A468-69.

               3.  Doody R, Clark C, Farlow M, et al. Chronic Donepezil Treatment is Associated with Slowed
                    Cognitive Decline in Alzheimer's disease patients. Neurobiology of Aging 1998;19(Suppl 4):S303.


               4.  Doraiswamy PM, Anand R, and HR. Cognitive effects of rivastigmine in patients with mild to
                    moderate alzheimer's disease compared to those with moderately-severe to severe AD. Clinical
                    Neuropsychological Assessment 2000;1(6):12.

               5.  Doraiswamy PM, Anand R, and HR. Long term cognitive effects in alzheimer's disease patients
                    stratified by vascular risk score and treated for 1 year with rivastigmine. Clinical Neuropsychological
                    Assessment 2000;1(6):14.

               6.  Engedal K, Soininen H, Verhey F, Waldemar G, Winblad B, Wimo A, et al. Donepezil improved or
                    stabilized cognition over one year in patients with mild and moderate alzheimer's disease. Journal of
                    the European College of Neuropsychopharmacology (Abstracts of the 13th ECNP Congress,
                    Munich, September 9-13, 2000) 2000;10(Supplement 3):S368.

               7.  Farlow M, Tariot P, Grossberg G, Gergel I, Graham S, Jin J. Memantine/donepezil dual therapy is
                    superior to placebo/donepezil therapy for treatment of moderate to severe Alzheimer's disease.
                    Neurology 2003;60(Suppl 1):A412.

               8.  Froelich L, Gertz HJ, Heun R, Heuser I, Jendroska K, Kornhuber J, et al. Donepezil for alzheimer's
                    disease - the donald study - a multicenter 24 weeks clinical trial in germany. Journal of the European
                    College of Neuropsychopharmacology (Abstracts of the 13th ECNP Congress, Munich, September
                    9-13, 2000) 2000;10(Supplement 3):S360.

               9.  Grimley EJ, Wilcock GK, Whitehead A, Birks J, Perdomo C, Pratt R. Donepezil: a meta-analysis of
                    individual patient data from randomised controlled trials in the treatment of patients with mild to
                    moderate alzheimer's disease. JNS 2001;187(Suppl. 1).

               10.  Mastey V, Wimo A, Winblad B, Haglund A, Jacobson L, Miceli R, et al. Donepezil reduces the time
                    caregivers spend providing care: results of a one-year, double-blind, randomized trial in patients with
                    mild to moderate Alzheimer's disease. 14th Annual Meeting of the American Association for
                    Geriatric Psychiatry; 2001 23rd-26th February; San Francisco, CA, USA 2001.

               11.  McRae T, Knopman D, Duttagupta S, Ieni J, Provenzano G. Donepezil delays time to nursing home
                    placement in patients with Alzheimer's disease. 14th Annual Meeting of the American Association
                    for Geriatric Psychiatry; 2001 23rd-26th February; San Francisco, CA, USA 2001.

               12.  McRae T, Knopman D, Mastey V, Ieni J, Provenzano G. Donepezil is strongly associated with
                    delayed nursing home placement in patients with alzheimer's disease. JNS 2001;187(Suppl. 1).



                 Alzheimer's Drugs                                                              Page 202 of 205
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