Page 331 - Drug Class Review
P. 331
Final Report Update 1 Drug Effectiveness Review Project
Domain / Scale Description
Function Activities of daily living (basic and instrumental)
Alzheimer’s Disease Cooperative 54-pt. scale (higher scores better)
Study Activities of Daily Living Informant rated interview of 27 basic and instrumental
(ADCS-ADL) ADL’s used in mild – moderate AD; a subgroup of 19
validated items has been used in moderate-severe AD
Disability Assessment for 100-pt. scale (higher scores better)
Dementia (DAD) Informant rated interview of 17 basic and 23 instrumental
ADL’s; initiation, organization, and planning distinguished
Bristol Activities of Daily Living 60-pt. scale (higher scores worse)
Scale (Bristol ADL) Informant rated interview of 20 items (10 ADL’s, 10
IADL’s) each rated on a 0-3 pt. scale
Behavior Mood , behavior, personality alterations, etc.
Neuropsychiatric Inventory (NPI) 144-pt. scale (higher scores worse)
Informant interview of 12 symptom domains rated on a
12-pt. scale based on Frequency (0-4) x Severity (0-3)
Behavioral symptoms in 75-pt. scale (higher scores worse)
Alzheimer’s disease (BEHAVE- Informant interview of 25 behavioral symptoms rated on a 0-3
AD) pt. scale
Alzheimer's Drugs Page 198 of 205
