Page 276 - Drug Class Review
P. 276

Page 168 of 205
             Drug Effectiveness Review Project



                                              Nausea   4-10%   17-22%   13%      40-44%   48-50%

















                                              Diarrhea   6-10%   13-17%   12%      13-19%   17%















                                Placebo-controlled trials of DON, GAL, and RIV

                                              Vomiting   3-10%   6-16%   6%      17-26%   27-34%















                                              Discontinuation   7%   15%   7%   16%   27%   26%











                                                                     No           No           N/A












             Final Report Update 1     Authors: Gauthier   Year: 2001   CHARACTERISTICS OF   INTERVENTIONS:         MAIN RESULTS:   DON 5mg/d   DON 10mg/d   GAL 16mg/d   GAL 24mg/d   GAL 32mg/d   RIV 6-12mg/d   COMPREHENSIVE  LITERATURE SEARCH   STRATEGY:     STANDARD METHOD OF  APPRAISAL OF STUDIES:         QUALITY RATING:            Alzheimer's Drugs
   271   272   273   274   275   276   277   278   279   280   281