Page 276 - Drug Class Review
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Drug Effectiveness Review Project
Nausea 4-10% 17-22% 13% 40-44% 48-50%
Diarrhea 6-10% 13-17% 12% 13-19% 17%
Placebo-controlled trials of DON, GAL, and RIV
Vomiting 3-10% 6-16% 6% 17-26% 27-34%
Discontinuation 7% 15% 7% 16% 27% 26%
No No N/A
Final Report Update 1 Authors: Gauthier Year: 2001 CHARACTERISTICS OF INTERVENTIONS: MAIN RESULTS: DON 5mg/d DON 10mg/d GAL 16mg/d GAL 24mg/d GAL 32mg/d RIV 6-12mg/d COMPREHENSIVE LITERATURE SEARCH STRATEGY: STANDARD METHOD OF APPRAISAL OF STUDIES: QUALITY RATING: Alzheimer's Drugs