Page 275 - Drug Class Review
P. 275
Drug Effectiveness Review Project
Placebo-controlled trials of DON, GAL, and RIV
Vomiting Nausea Diarrhea 4-10% 6-10% 3-10% 17-22% 13-17% 6-16% 13% 12% 6% 40-44% 13-19% 17-26% 48-50% 17% 27-34% Page 168 of 205
Discontinuation 7% 15% 7% 16% 27% 26%
No No N/A
Final Report Update 1 Authors: Gauthier Year: 2001 CHARACTERISTICS OF INTERVENTIONS: MAIN RESULTS: DON 5mg/d DON 10mg/d GAL 16mg/d GAL 24mg/d GAL 32mg/d RIV 6-12mg/d COMPREHENSIVE LITERATURE SEARCH STRATEGY: STANDARD METHOD OF APPRAISAL OF STUDIES: QUALITY RATING: Alzheimer's Drugs