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Drug Effectiveness Review Project
Alzheimer Drugs Authors: Whitehead et al. 33 Year: 2004 Medical Research Council Study design: Meta-analysis (individual patient data) Number of patients: 2,376 To evaluate the efficacy and tolerability of DON (5 and 10 mg/d) compared with placebo in alleviating manifestations of mild to moderate AD Published and unpublished data of 10 RCTs Up to 1999 All randomized, double-blind, placebo-controlled, parallel-group studies from the DON clinical development program undertaken and completed as of 20 December 1999, in which DON was administered for more than one day at 5 and 10 mg/d Pa
Final Report Update 1 Efficacy/Effectiveness STUDY: FUNDING: DESIGN: AIMS OF REVIEW: STUDIES INCLUDED IN META-ANALYSIS TIME PERIOD COVERED: CHARACTERISTICS OF INCLUDED STUDIES: CHARACTERISTICS OF INCLUDED POPULATIONS: Alzheimer's Drugs
