Page 135 - LECTURE NOTES
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preferable to perform tests with an accompanying control solution. The diameter of in
duration is measured at 48 and 72 hours.
Positive reaction: The reaction is considered positive when the area of indurations is
5mm in diameter or more.
A positive reaction may be found in many persons from endemic areas who show no
visible skin lesions but have been exposed to infection (test remains positive for life). A
positive leishmanin test in children under 10 years of age from endemic areas is highly
suggestive of the disease.
In persons entering an endemic area for the first time, the development of skin lesions
and positive test indicates cutaneous leishmaniasis.
Negative reaction: a negative reaction may be found in some 15% of patients with
uncomplicated cutaneous leishmaniasis. There are no significant cross-reactions with
other diseases.
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