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346 REFERENCES

Huson, S. M., Compston, D. A., Clark, P., and Harper, P. S. 1989. A genetic study
of von Recklinghausen neurofibromatosis in south east Wales. I. Prevalence,
fitness, mutation rate, and effect of parental transmission on severity. Jour-
nal of Medical Genetics 26:704–711.
Issa, J. P. 2000. CpG-island methylation in aging and cancer. Current Topics in
Microbiology and Immunology 249:101–118.
Issa, J. P. 2004. Opinion: CpG island methylator phenotype in cancer. Nature
Reviews Cancer 4:988–993.
Iversen, O. H. 1995. Of mice and men: a critical reappraisal of the two-stage
theory of carcinogenesis. Critical Reviews in Oncogenesis 6:357–405.
Janes, S. M., Lowell, S., and Hutter, C. 2002. Epidermal stem cells. Journal of
Pathology 197:479–491.
Jass, J. R. 2003. Serrated adenoma of the colorectum: a lesion with teeth. Amer-
ican Journal of Pathology 162:705–708.
Jass, J. R., Whitehall, V. L., Young, J., and Leggett, B. A. 2002a. Emerging concepts
in colorectal neoplasia. Gastroenterology 123:862–876.
Jass, J. R., Young, J., and Leggett, B. A. 2002b. Evolution of colorectal cancer:
change of pace and change of direction. Journal of Gastroenterology and
Hepatology 17:17–26.
Jiang, W., Ananthaswamy, H. N., Muller, H. K., and Kripke, M. L. 1999. p53 pro-
tects against skin cancer induction by UV-B radiation. Oncogene 18:4247–
4253.
Jonason, A. S., Kunala, S., Price, G. J., Restifo, R. J., Spinelli, H. M., Persing, J. A.,
Leffell, D. J., Tarone, R. E., and Brash, D. E. 1996. Frequent clones of p53-
mutated keratinocytes in normal human skin. Proceedings of the National
Academy of Sciences of the United States of America 93:14025–14029.
Jones, P. A., and Baylin, S. B. 2002. The fundamental role of epigenetic events
in cancer. Nature Reviews Genetics 3:415–428.
Karpowicz, P., Morshead, C., Kam, A., Jervis, E., Ramunas, J., Cheng, V., and
van der Kooy, D. 2005. Support for the immortal strand hypothesis: neural
stem cells partition DNA asymmetrically in vitro. Journal of Cell Biology
170:721–732.
Kastan, M. B., and Bartek, J. 2004. Cell-cycle checkpoints and cancer. Nature
432:316–323.
Kemp, C. J., Donehower, L. A., Bradley, A., and Balmain, A. 1993. Reduction
of p53 gene dosage does not increase initiation or promotion but enhances
malignant progression of chemically induced skin tumors. Cell 74:813–822.
Kim, B. G., Li, C., Qiao, W., Mamura, M., Kasperczak, B., Anver, M., Wolfraim,
L., Hong, S., Mushinski, E., Potter, M., Kim, S. J., Fu, X. Y., Deng, C., and Let-
terio, J. J. 2006. Smad4 signalling in T cells is required for suppression of
gastrointestinal cancer. Nature 441:1015–1019.
Kim, J. Y., Tavare, S., and Shibata, D. 2005. Counting human somatic cell repli-
cations: methylation mirrors endometrial stem cell divisions. Proceedings of