Page 452 - 16Neonatal Jaundice_compressed
P. 452

Appendix H: Evidence tables


              Bibliographic details  Study type &   Patient characteristics   Results                 Reviewers Comments              Bibliographic details
                             Evidence level

              Author:        Study Type:     Diagnosis                 Once TsB reached criteria for phototherapy   Duration of phototherapy:
                                                                               19
              Barak M        RCT             Hyperbilirubinaemia       (AAP 2004)  the baby was given phototherapy   Group 1: 22 ± 13 hours
                                                                       to two group for when phototherapy should be
              Year:          Evidence Level:   Criteria:               discontinued                   Group 2: 27 ± 12 hours
              2009           1 ++            GA > 36 weeks
                                             BW > 2500 g               Group 1                        Rebound level – 10 hours:
              Country:                                                 TsB ≥ 17 micromol/litre below threshold   Group 1: 1.8 ± 25.6 micromol/litre
              Israel                         Setting                   Group 2
                                             Medical Center            TsB  ≥ 51 micromol/litre below threshold   Group 2: 4.8 ± 22.2 micromol/litre
              ID:
                125
                                             Randomisation method:                                    Rebound level – 28 hours:
                                             Computer-generated block                                 Group 1: 19.1 ± 29.1 micromol/litre
                                             randomisation.
                                             Sequence was concealed until                             Group 2: 11.6 ± 36.4 micromol/litre
                                             allocation was completed
                                                                                                      Number requiring PT
                                             Blinding:                                                Group 1: 5/25 (20.0%)
                                             Parents                                                  Group 2: 5/27 (18.5%)

                                             Demographics:
                                             Sample size: 52
                                             Gender (M/F): 27/25
                                             Mean GA:
                                             38.7 ± 1.6 weeks
                                             Mean BW:
                                             3302 ± 453 g
                                             Mean TsB:
                                             252 ± 36 micromol/litre






















                                                                                                                                                     299
   447   448   449   450   451   452   453   454   455   456   457