Page 350 - 16Neonatal Jaundice_compressed
P. 350

Neonatal jaundice


              Bibliographic details   Study type &   Patient characteristics                Results                           Reviewers Comments
                                  Evidence level
                                                  Ethnicity: Not reported                   49/125 (39.2%)
                                                  Breastfeeding:
                                                  Onset of Jaundice: Days 0 – 7             Infection: 1/125 (0.8%)
                                                  Duration of jaundice:
                                                                                            Idiopathic: 35/125 (28%)
                                                  Exclusion: None
                                                                                            Exchange Transfusion (n = 53)
                                                                                            ABO incompatibility: 15/53 (20.6%)

                                                                                            Rh incompatibility:1/53 (1.9%)

                                                                                            G6PD deficiency:
                                                                                            21/53 (39.6%)

                                                                                            Infection: 0/53 (0%)

                                                                                            Idiopathic: 11/53 (20.7%)
              Author: Ho K        Study type:     Diagnosis: Jaundice                       Mean bilirubin levels             Authors report a drop in number of
                                  Retrospective chart   Criteria: TSB ≥ 256 micromol/litre   TSB: Not reported                G6PD cases requiring exchange
              Year: 1991          review          Setting: Hospital                                                           transfusion on new guidelines that
                                                                                            ABO incompatibility: 73/270 (27.0%)   specified that G6PD be screened for at
              Country: Singapore   Evidence level: 3   Sample Size: 270                                                        birth and deficient babies be kept in
                                                  Mean GA: Not reported                     Rh incompatibility:1/270 (0.4%)    hospital for a minimum of 2 weeks
                   96
              Ref ID:                             Mean BW: Not reported
                                                  Gender M/F: Not reported                  G6PD deficiency: 18/270 (6.7%)
                                                  Ethnicity: Not reported
                                                  Breastfeeding: Not reported               Infection: Not reported
                                                  Onset of Jaundice: Not reported
                                                                                            Idiopathic: Not reported
                                                  Exclusion: None
                                                                                            Exchange Transfusion (n = 46)
                                                                                            ABO incompatibility: 17/46 (37.0%)

                                                                                            Rh incompatibility: 1/46 (2.2%)

                                                                                            G6PD deficiency:
                                                                                            2/46 (4.3%)

                                                                                            Infection: 8/46 (17.4%)

                                                                                            Idiopathic: 6/46(13.0%)
              Author: Ahmed H     Study type:     Diagnosis: Jaundice                       Mean bilirubin levels             Incidence of infection higher in babies
                                  Case control study   Criteria: TSB ≥ 171 micromol/litre   TSB: 312 micromol/litre           readmitted from home
              Year: 1995                          Setting: Hospital
                                  Evidence level: 2 -                                       ABO incompatibility: 24/102 (23.5%)
              Country: Nigeria                    Sample Size: 102
                                                  Mean GA: Not reported                     Rh incompatibility: 0/102 (0%)
                   92
              Ref ID:                             Mean BW: Not reported


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