Page 342 - 16Neonatal Jaundice_compressed

Neonatal jaundice

Bibliographic details Study type & Patient characteristics Results Reviewers Comments
Evidence level

Rh incompatibility: 108/248 (43.5%)

G6PD deficiency:
2/248 (0.8%)

Infection: 2/248 (0.8%)

Author: Sodeinde O Study type: Diagnosis: Jaundice Mean bilirubin levels Not all subjects tested for ABO
Case control study Criteria: TSB ≥ 205 micromol/litre TSB: Not reported incompatibility or infection
Year: 1995 Setting: Hospital
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Evidence level: 2 ABO incompatibility: 40/150 (26.7%)
Country: Nigeria Sample Size: 327
Mean GA: Not reported. 87 (26.5%) were preterm Rh incompatibility: 3/150 (2.0%)
Ref ID: < 37 weeks
85
Mean BW: 2.73 ± 0.74 kg G6PD deficiency: 109/327 (33.3%) (P value
Gender M/F: Not reported < 0.0087)
Ethnicity: Not reported Infection: 38/217 (17.5%)
Breastfeeding: Not reported
Onset of Jaundice: Not reported Idiopathic: Not reported

Exclusion: None
Author: Yeung C Study type: Diagnosis: Jaundice Mean bilirubin levels
Case series Criteria: TSB ≥ 171 micromol/litre TSB: Not reported
Year: 1973 Setting: Hospital
Evidence level: 3 ABO incompatibility: 414/1811(22.8%)
Country: China Sample Size: 1811
Mean GA: Not reported Rh incompatibility: Not reported
Ref ID: Mean BW: Not reported. 65 (3.6%) were preterm
90
< 38 weeks G6PD deficiency: 241/1811 (13.3)
Gender M/F: 1054/755
Ethnicity: Not reported Infection: Not reported
Breastfeeding: Not reported
Onset of Jaundice: Day 0 - 10 Idiopathic: Not reported

Exclusion: None
Exchange transfusion (n = 581)
ABO incompatibility: 157/581 (27.0%)

G6PD deficiency: 13/581 (22.4%)

Infection: Not reported

Idiopathic: Not reported

Kernicterus (n = 156)
ABO incompatibility: 51/156 (32.7%)

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