Page 174 - Screening for Cervical Cancer: Systematic Evidence Review

Chapter III. Results

Table 10. HPV Testing Among Women with Abnormal Pap Test Results*
Prevalence of Prevalence of Prevalence of
Article Population/ Referral Pap LSIL (%) HSIL (%) Carcinoma (%)
454 indigent Texan women
Adam et referred for colposcopy after LSIL = 55.3 HGSIL = 14.5 4 cases invasive
71
al., 1998 cancer = 0.40
ASCUS or LSIL
Bollen et 190 consecutive Dutch women LSIL = 57.8 HSIL = 29.5 No cases
66
al., 1997 with mild or moderate dysplasia
Herrington 167 British women referred for “wart virus CIN 2 = 7.2
et al., colposcopy for low grade cytologic changes” = 37.7 CIN 3 = 16.8 No cases
69
1995 findings ( ≤ CIN 1) CIN 1 = 15.0
Hillemanns
et al., 247 German colposcopy patients CIN 1 = 7.3 CIN 2/3= 15.4 2 cases invasive
cancer = 0.81
72
1999
Manos et 973 US HMO patients with LSIL = 12.8 HSIL = 6.7 1 case invasive
68
al. 1999 ASCUS cancer = 0.1
Sigurdsson 358 Icelandic women referred for CIN 2 = 15.9 7 cases invasive
et al., colposcopy CIN 1 = 16.5 CIN 3 = 36.6 cancer = 2.0
67
1997
Sun et al., 520 US or Canadian women LSIL = 31.0 HSIL = 18.8 7 cases invasive
73
1995 referred for colposcopy cancer = 1.3

*HPV, human papilloma virus; LSIL, low-grade squamous intraepithelial lesion; HSIL, high-grade squamous intraepithelial
lesion; CIN, cervical intraepithelial neoplasia

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