Page 107 - Screening for Cervical Cancer: Systematic Evidence Review
P. 107

Appendix C.  Evidence Tables



               Evidence Table 1A.  Screening Among Older Women (cont'd)

                                 Screening    Outcomes &                                           Quality
                 Participants    Program        Measures             Relevant Results          Consideration
               N = 41,212     No systematic  Primary        AGE:                               Denom=2
               women with     screening      outcome =      Incidence rate for CIN 3 and cancer   Attrition=0
               negative Pap at  program in   CIN 3 or       was highest among women aged 25-   Indications=2
               entry          place;         cervical cancer  29 and decreased with age thereafter:  Interval=2
                              centralized                                                      Age=2
               Born 1920-69;  recall for follow- 396 incident in  Age        Person          Cases   Relevance=1
               no CIN or      up of abnormal  175,673 person                  Years       10,000 PYR   Standard=1
               cervical cancer  Paps only    yrs            20-24     33,663               68   Score=10
               hx; no hx of                                 25-29     34,349             136
               cervical biopsy                              30-34     27,325               87   Grade=Fair
                                                            35-39     27,325               44
                                                            > 40       48,666               61

                                                            INTERVAL:
                                                            Age-Adjusted Risk of CIN III/Cancer
                                                            Years      RR           (95% CI)
                                                            < 1           1.0
                                                            1              1.5          (1.2, 2.0)
                                                            2              2.4          (1.8, 3.3)
                                                            3+          12.2        (9.2, 16.3)
















































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