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      question should be whether he or she is taking an adequate dose, as
      that will dominate or undermine other factors in producing
      improvement.

      The second milestone was the publication of an Institute of Medicine
      (IOM) report on the Federal Regulation of Methadone Treatment
      (Rettig & Yarmolinsky, 1995).  The IOM is chartered by the National
      Academy of Sciences.  This highly prestigious committee concluded
      that the effectiveness of methadone treatment is well established, but
      overregulation created barriers to access and implementation of good
      practices.  They examined the impact of diversion, the issue that
      inspired much of the early regulations. After careful study, they
      concluded that the risks of diversion and misuse did not warrant the
      unusual level of regulation, and that these needed to be modified to
      promote better access and good care.

      The third milestone was the convening of an NIH Consensus
      Development Conference in 1997 (National Consensus Development
      Panel on Effective Medical Treatment of Opiate Addiction, 1998).
      This process has been crafted by NIH to address controversial topics
      in medicine and public health in an unbiased, impartial manner.  An
      independent panel of non-federal professionals in health fields is
      convened to hear reports by experts, who present research on specific
      aspects of the topic.  After discussion, the panel issues findings and
      recommendations.  The panel reviewed the existing medical literature
      and attended a series of expert presentations, and then strongly
      recommended broader access to methadone treatment, through
      reduction of regulatory barriers and  active leadership in addressing
      stigma and other issues.

      Conclusion

      In summary, methadone treatment has been exhaustively studied from
      a variety of perspectives.  Although inappropriate policies and
      practices can undermine its effectiveness, when properly implemented
      it is a powerful tool to bring improvement in measures of public health
      and safety.
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