Page 7 - The Flying Publisher Guide to Hepatitis C Treatment

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Abbreviations

ACR: acute cellular rejection INR: international normalized
AEs: Adverse side effects ratio
ALT: alanine aminotransferase IR: insulin resistance
ANC: absolute neutrophil IU: international unit
count LT: liver transplant
AST: aspartate MELD: Model for End-Stage
aminotransferase Liver Disease
BMI: body mass index MMF: mycophenolate mofetil
CP: Child-Pugh NAT: nucleic acid tests
Anti-HCV: antibody to PCR: polymerase chain
hepatitis C virus reaction
cEVR: complete early virologic PegIFN: pegylated interferon
response pEVR: partial early virologic
CIFN: consensus interferon response
CHC: chronic hepatitis C PKR: interferon-inducible
DAA: direct-acting antivirals proteinkinase
DILI: drug-induced liver PT: prothrombin time
injuries QoL: quality of life
EMEA: European Medicines QALY: quality adjusted life-
Agency year
EoTR: end of treatment RBV: ribavirin
virologic response RGT: response-guided therapy
EVR: early virologic response RVR: rapid virologic response
FDA: US Food and Drug SNP: single nucleotide
Administration polymorphism
HBV: hepatitis B virus SoC: standard of care antiviral
HCV: hepatitis C virus therapy
HCV RNA: ribonucleic acid of SSRI: selective serotonin
hepatitis C virus reuptake Inhibitor
HCC: hepatocellular carcinoma STAT-C: Specifically targeted
HIV: human immunodeficiency antiviral therapy for HCV
virus SVR: sustained virologic
IDUs: injecting drug users response
IFN: interferon TSH: thyroid stimulating
IL28B: interleukin 28B hormone
IMPDH: inosine ULN: Upper limit of normal
monophosphate VL: viral load
dehydrogenase