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Chapter 1

            Nervous System


                 The nervous system, along with the endocrine system, serves as the primary control center of the
            body working below the level of consciousness. For example, the hypothalamus of the brain is where
            the body's "thermostat" is found. The hypothalamus also stimulates the pituitary gland to release
            various   hormones   that   control   metabolism   and   development   of   the   body.   The   sympathetic   and
            parasympathetic divisions of the nervous system alternatively stimulate or inhibit various bodily
            responses (such as heart rate, breathing rate, etc) to help maintain proper levels. It also controls
            contractions like the arrector pili muscles (involved in thermoregulation) and skeletal muscles, which in
            addition to moving   the  body,   also   cause  bone  thickening   and   maintenance,   which   affects  bone
            composition. The nervous system also regulates various systems such as respiratory (controls pace and
            depth of breathing), cardiovascular system (controls heart rate and blood pressure), endocrine organs
            (causes secretion of ADH and oxytocin), the digestive system (regulates the digestive tract movement
            and secretion), and the urinary system (it helps adjust renal blood pressure and also controls voiding the
            bladder). The nervous system is also involved in our sexual behaviors and functions.



            Endocrine System


                 The endocrine system consists of glands which secrete hormones into the bloodstream. Each
            hormone has an effect on one or more target tissues. In this way the endocrine system regulates the
            metabolism and development of most body cells and body systems. To be more specific, the Endocrine
            system has sex hormones that can activate sebaceous glands, development of mammary glands, alter
            dermal blood flow and release lipids from adipocytes and MSH can stimulate melanocytes on our skin.
            Our   bone   growth   is   regulated   by   several   hormones,   and   the   endocrine   system   helps   with   the
            mobilization of calcitonin and calcium. In the muscular system hormones adjust muscle metabolism,
            energy production, and growth. In the nervous system hormones affect neural metabolism, regulate
            fluid/electrolyte balance and help with reproductive hormones that influence CNS development and
            behaviors. In the Cardiovascular system we need hormones that regulate the production of RBC's,
            elevate and lower blood pressure. Hormones also have anti-inflammatory affects as well as stimulates
            the lymphatic system. In summary, the endocrine system has a regulatory effect on basically every
            other body system.



            Integumentary System


                 The integumentary system is involved in protecting the body from invading microbes (mainly by
            forming a thick impenetrable layer), regulating body temperature through sweating and vasodilation, or
            shivering and piloerection (goose bumps), and regulating ion balances in the blood. Stimulation of mast
            cells also produce changes in blood flow and capillary permeability which can effect the blood flow in
            the body and how it is regulated. It also helps synthesize vitamin D which interacts with calcium and
            phosphorus absorption needed for bone growth and maintenance for example if we ever broke a bone
            and it needs repair. Hair on the skin guards entrance into the nasal cavity or other orifices preventing
            invaders of getting further into our bodies. Our skin also helps maintain balance by excretion of water
            and other solutes (i.e.) the keratinized epidermis limits fluid loss through skin. Thus saying it provides
            mechanical   protection   against   environmental   hazards.   We   need   to   remember   that   our   skin   is
            integumentary, it is our first line of defense and to keep it balanced takes work.






            8 | Human Physiology
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