Page 90 - 78 glossary of hivaids-related terms_opt
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MTN
See: Microbicide Trials Network
M-Tropic Virus
See: R5-Tropic Virus
See Also: CCR5
Mucocutaneous
Relating to mucous membranes and the skin. Examples of
mucocutaneous areas include the mouth, lips, eyes, vagina, and
anal area.
Multicenter AIDS Cohort Study (MACS)
An ongoing study of HIV infection in homosexual and bisexual
men. The study is cofunded by the National Institute of Allergy
and Infectious Diseases (NIAID); the National Cancer Institute
(NCI); and the National Heart, Lung, and Blood Institute (NHLBI)
and is conducted at four clinical centers. Information about the
M natural history of HIV disease, the impact of treatment on disease
progression, the role of genetic factors, and other long-term therapy
issues are continually reported from study evaluations.
Multi-Class Antiretroviral Therapy
See: Highly Active Antiretroviral Therapy (HAART)
Multiple Drug-Resistant Tuberculosis (MDR-TB)
A tuberculosis (TB) infection that does not respond to two or more
standard anti-TB drugs. MDR-TB usually occurs when inadequate
or improper treatment allows the bacteria that cause TB to continue
multiplying and become drug resistant.
See Also: Tuberculosis (TB)
Mutation
A change or adaptation, such as in a virus, that can be passed
down to future generations of virus. Mutations can occur only when
a virus is actively replicating, and not when anti-HIV drugs have
suppressed the viral load to an undetectable level. If HIV replication
88 HIV/AIDS Glossary