Page 118 - 78 glossary of hivaids-related terms_opt
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R5-Tropic Virus
Also known as M-tropic virus. A strain of HIV that uses the
chemokine receptor CCR5 as a coreceptor to bind to and infect
human cells. HIV is usually R5-tropic at early stages of infection, but
the virus can switch to a different coreceptor (for example, CXCR4)
as the disease progresses.
See Also: X4-Tropic Virus
CCR5
Chemokines
Coreceptor
Randomized Trial
A type of clinical trial in which participants are assigned by chance
to one of two or more treatment or placebo groups. A randomized
trial design helps researchers gather meaningful information and
make valid statistical calculations.
See Also: Clinical Trial
Placebo
Rapid Test
A type of HIV-1 enzyme-linked immunosorbent assay (ELISA) that
can detect antibodies to HIV in the blood in less than 30 minutes
with greater than 99% sensitivity and specificity. A positive rapid test
result should be confirmed by an HIV Western blot test.
See Also: Enzyme-Linked Immunosorbent Assay (ELISA)
R Western Blot
Rebound
See: Viral Rebound
Receptor
A protein on the surface of a cell that serves as a binding site for
substances outside the cell, such as HIV floating free in the blood.
See Also: Coreceptor
CD4 Receptor
116 HIV/AIDS Glossary