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296  Congenital Diaphragmatic Hernia and Diaphragmatic Eventration
                                                               Surgery
                                                               For  left-sided  lesions,  the  approach  can  be  either  abdominal  or  tho-
                                                               racic. For lesions on the right side, a thoracic approach is preferential.
                                                               The thoracic approach is through a posterolateral 7th to 9th rib space.
                                                               The  abdominal  approach  is  usually  subcostal.  Bilateral  cases  can  be
                                                               approached through a transverse upper abdominal incision. A thoraco-
                                                               scopic approach may be used if skills and resources are available.
                                                                 The key features of the operation are:
                                                                • Confirmation of the diagnosis (versus CDH).
                                                                • Plication of the diaphragm by using several rows of pledgeted non-
                                                                 absorbable sutures to obtain a relatively flat diaphragm.
                                                                • Bites of the diaphragm are taken at suitable intervals (~1 cm) in a
                                                                 radial fashion (usually, three or four rows of sutures are needed).
                                                                • These sutures can be placed individually without tying, and tied
                                                                 sequentially at the end.
                                                                • Identification and avoidance of the branches of the phrenic nerve,
                                                                 if possible.
        Figure 45.7: Right-sided eventration of the diaphragm.
                                                                • A chest drain may be left after a thoracic approach, although this is
                                                                 not mandatory.
                                                                 A postoperative chest x-ray is suggested to check the position of the
                                                               diaphragm (Figure 45.9).
                                                               Postoperative Complications
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                                                               There are relatively few postoperative complications with this surgery.
                                                               Trauma to the intestines and liver during a thoracic approach is avoided
                                                               by careful placement of sutures into the diaphragm. Postoperative pneu-
                                                               mothorax is also uncommon, and usually resolves with chest drainage.
                                                               Adhesive intestinal obstruction is possible after an abdominal approach.
                                                               Recurrence is possible, but is much less common than in CDH.
                                                               Prognosis and Outcomes
                                                               The  prognosis  is  very  good  in  the  absence  of  other  anomalies.
                                                               Respiratory mechanics are improved by plication, with increased tidal
                                                               volume and vital capacity and improvement of symptoms. In a follow-
                                                               up study 1 to 5 years postplication, there was no recurrence of symp-
                                                               toms,  with only one of nine patients having an elevated diaphragm. In
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                                                               the rest, the diaphragm was flat but immobile.
                                                               Prevention
                                                               Avoidance of the phrenic nerve during surgery and procedures that put
                                                               it at risk is preventive in cases due to phrenic nerve injury.
        Figure 45.8: Left-sided eventration of the diaphragm.              Evidence-Based Research
                                                               Table 45.1 presents a meta-analysis that evaluates the use of ECMO in
                                                               infants with CDH.






















        Figure 45.9: Postoperative chest x-ray after right-sided eventration repair for the
        same patient as in Figure 45.7.
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