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                                                  Haematogenous Osteomyelitis and Septic Arthritis  137

          the essential modality in the treatment of all stages of osteomyelitis in
          LWATs.
            Stage 1 HO is the most important stage for expeditious treatment,
          which  may  result  in  cure  of  the  acute  process  and  also  prevent
          progression to chronic osteomyelitis. In acute HO, the operative goal
          is to decompress all pus under pressure. This involves decompression
          of  both  subperiosteal  and  intramedullary  pus.  Decompression  must
          be adequate enough to prevent reaccumulation. Antibiotics are highly
          recommended  in  the  initial  treatment  of  stage  1  HO  to  manage  the
          systemic  sepsis.  Antibiotics  are  also  recommended  for  a  2–6  week
          period of treatment to prevent progression to chronic osteomyelitis.
            Whenever  HO  has  progressed  to  stage  2,  x-ray  changes  already
          indicate  nonviable  bone  while  systemic  and  local  sepsis  remains.
          Treatment  for  stage  2  also  involves  prompt  decompression  and
          antibiotics to treat the systemic sepsis. Usually, the sequestrum is not
          well developed, and extensive debridement should be avoided because   Figure 22.3: Stage 3 HO of the humerus in a 5-year-old child with (A)
          it is very difficult to differentiate viable from nonviable bone at this   spontaneous extruding sequestrum, as seen on (B) a “road map” x-ray.
          time. There is no documentation that prolonged antibiotics in stage 2
          will prevent progression to chronic HO, but if antibiotics are available,
          they should be used for at least 2 weeks after resolution of the acute
          process.
            Most  children  in  LWATs  present  in  stage  3  or  4.  When  HO  has
          reached  stage  3,  antibiotics  have  little  role  in  treatment.  An  x-ray
          serves  as  a  “road  map”  (Figure  22.3)  and  is  essential  in  planning
          proper treatment for both stages 3 and 4. With adequate debridement
          of sequestra, there is a chance of eventual healing of stage 3 HO even
          without antibiotics (Figures 22.4 and 22.5). The treatment for stage 4
          HO (Figure 22.6) differs from the treatment for stage 3 only in the need
          for short-term antibiotics until the systemic sepsis has been controlled.
          Prolonged systemic antibiotic administration after total debridement of
          sequestra has not been proven effective in preventing further episodes
          of chronic HO.
          Operative Techniques
          This  section  considers  in  more  detail  the  operative  techniques  used
          in the treatment of all stages of HO. An optimal basic instrument tray   Figure 22.4: Stage 3 HO of the fibula with (A) spontaneous extrusion of the
          consists  of  the  following  instruments:  soft  tissue  basic  instruments   sequestrum. (B) After sequestrectomy, complete healing is achieved without
          (haemostat, scalpel, tissue forceps, needle holder, scissors); soft tissue   antibiotics.
































                    Figure 22.5: Stage 3 HO of the tibia in a 7-year-old male: (A) initial presentation; (B) tibia after removing a cortical trough, which showed that the tibial
                    shaft was completely nonviable; (C) appearance after giant sequestrectomy and healing by secondary intention without using antibiotics; (D) child at
                    time of discharge; (E) x-ray at time of discharge; (F) same patient 15 years later; (G) x-ray 15 years later.
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