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58  Anaesthesia and Perioperative Care
        Laryngeal Mask Airways                                           Laryngoscopy and Intubation
        LMAs (Figure 10.6) are useful airway management tools. They are less   The  airway  should  be  ventilated  in  all  but  the  shortest  of  procedures
        traumatic than endotracheal tubes and do not require laryngoscopy to   because the paediatric airway is very prone to obstruction during anaes-
        insert. They do not, however, protect against regurgitation and aspira-  thesia. For neonates and infants, a slight external pressure on the larynx
        tion. Sizes 1, 1½, 2, 2½, and 3 can be used in children from 2 months   helps to bring the glottis into view. A small leak should be allowed around
        to 12 years of age, according to the weight of the child.  the tube to prevent oedema formation and postoperative airway obstruc-
                                                                                                3
        Endotracheal Tubes                                     tion, which may follow prolonged intubation.  If the patient is at risk of
        Endotracheal tubes used for children younger than 6 years of age are   aspiration, a pharyngeal gauze pack should be placed around the tube.
        usually uncuffed. Table 10.1 provides a guide for choosing an appropri-  A  gaseous  induction  using  100%  oxygen  with  halothane  is  the
        ate endotracheal tube.                                 technique of choice in small children and those with difficult airways.
                                                               The  aim  is  to  attain  a  plane  of  anaesthesia  that  is  deep  enough
        Mask Ventilation                                       to  allow  laryngoscopy.  Once  the  pupils  become  constricted  and
        Due to the neonate’s relatively large head, a small roll should be posi-  central,  laryngoscopy  and  orotracheal  intubation  can  be  performed.
        tioned under the shoulders to prevent hyperflexion of the head and align   Suxamethonium  at  a  dose  of  2  mg/kg  can  be  used  to  facilitate
        the axis of the mouth, pharynx, and larynx to allow for easy flow of air.   intubation.  Atropine  (0.02  mg/kg)  or  glycopyrrolate  (0.01  mg/kg)
        For the older child, no pillow or roll is needed. An appropriately sized   should  be  given  to  prevent  bradycardia  and  to  dry  secretions.  Both
        oropharyngeal airway can improve mask ventilation.     lungs should be auscultated for bilateral air entry after intubation, and
                                                               the endotracheal tube should be secured firmly in position.
                                                                 Signs of respiratory obstruction include an increase in respiratory
                                                               rate  (>50  per  minute  in  an  infant  and  30  per  minute  in  a  child);  a
                                                               “see-saw”  pattern  of  chest  and  abdominal  breathing  movements;
                                                               flaring of the alar nasi; and the use of accessory muscles of respiration
                                                               (sternomastoids, scalene muscles) resulting in suprasternal, intercostal,
                                                               and subcostal retraction.
                                                                 In  acute  airway  obstruction,  for  which  one  cannot  intubate  or
        Figure 10.4: Miller’s blades and handle.               ventilate,  cricothyrotomy  may  be  the  only  option.  Cricothyrotomy
                                                               is  difficult  in  a  small  child  and  carries  many  risks.  Where  difficult
                                                               tracheal intubation is anticipated, experienced help should be sought
                                                               beforehand.  There  are  fibre-optic  laryngoscopes  suitable  for  use  in
                                                               children, but this requires expertise and experience and is not an option
                                                               in emergency airway obstruction.
                                                                                Muscle Relaxants
                                                               Muscle relaxants are used to facilitate tracheal intubation and provide
                                                               muscle  relaxation  during  surgery,  thus  permitting  lighter  planes  of
                                                               anaesthesia and reducing the risk of cardiovascular depression. They
        Figure 10.5: Macintosh blade and handle.               are used in intraperitoneal, intrathoracic, and intracranial procedures.
                                                                 Muscle relaxants are classified into depolarising and nondepolarising
                                                               groups. Succinylcholine is the only depolarising neuromuscular blocker
                                                               in  use  today,  and  it  remains  the  agent  with  the  quickest  onset  and
                                                               shortest duration of action. Unfortunately, succinylcholine is associated
                                                               with  some  life-threatening  side  effects  (hyperkalaemia,  malignant
                                                               hyperthermia), and its use has reduced somewhat in recent years.
                                                                 Nondepolarising muscle relaxants are classified based on structure
                                                               and  mode  of  elimination.  The  benzoquinolones  are  atracurium,  cis-
                                                               atracurium, and mivacurium, which may be available in some African
                                                               urban centres. The first two are eliminated by Hoffmann degradation
                                                               and ester hydrolysis by nonspecific plasma esterases. Mivacurium is
         Figure 10.6 Laryngeal mask airways.                   metabolised by plasma cholinesterase.
                                                                 The aminosteroids (pancuronium, vecuronium, and rocuronium) are
                                                               metabolised in the liver, and their inactive end products are eliminated
        Table 10.1: Endotracheal tube sizes for children.
                                                               by the kidney.
         Age            Size of endotracheal tube (mm)
                                                                                   Monitoring
         Premature       2–2.5
                                                               The purpose of monitoring is to measure physiological variables and to
         Full-term newborn  3.0                                indicate trends of change, thus enabling corrective action to be taken.
                                                               The anaesthetist remains the most important monitor and must remain
         6–12 months    3.5
                                                               in close contact with the patient during all aspects of the anaesthetic.
                                                                 The precordial (or oesophageal) stethoscope is an invaluable monitor
         1–2 years      4–4.5
                                                               for many paediatric anaesthetists. It provides a direct way to continuously
         >2 years       4.5 + [age (in years) ÷ 4]             monitor heart rate and rhythm as well as breath sounds; it allows early
                                                               detection of changes in the rate and character of these sounds.
                                                                 The electrocardiogram (ECG) is useful for diagnosing rate-related
                                                               arrhythmias,  especially  bradycardia  and  supraventricular  tachycardia
                                                               (SVT). The ECG is an index of electrical activity. A normal waveform
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