Page 4 - Organogold Reactivity with Palladium, Nickel, and Rhodium: Transmetalation, Cross-Coupling, and Dual Catalysis
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Organogold Dual Metal Catalysis Hirner et al.
TABLE 2. Representative Pd-Catalyzed Carboauration Products
SCHEME 3. One-Pot Tandem Carboauration of Alkynes and Cross-Coupling Reaction a
a
Yellow-shaded box demarcates palladium-catalyzed carboauration. Unshaded portion shows palladium-catalyzed cross-coupling reactions of organogold compounds.
SCHEME 4. Proposed Mechanism for the Au and Pd Dual-Catalyzed Cyclization and Cross-Coupling Reaction
reaction forming 8a (Scheme 3, yellow-shaded box), the generated cross-coupled products 16ac in high conver-
addition of organohalides to the crude reaction mixture sion (Scheme 3). The organogold reagents participated in
606 ’ ACCOUNTS OF CHEMICAL RESEARCH ’ 603–613 ’ 2011 ’ Vol. 44, No. 8
