Page 302 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer

Appendix Table C1.9. Tumor characteristics—PSA

Author Database PSA groups 1980- 1985-89 1990-94 1995-99 2000-04 2005-10 Statistical Notes
Year (ng/ml) 84 analysis
PMID
64
Kindrick CaPSURE Median PSA 10.1 9.2 NR Additional
1998 at diagnosis (1992) (1997) information in
9817332 provided in the
single Figure of the
paper.
65
Cooperberg CaPSURE <4 9.6% 13.8% NR Additional
2002 4-10 46.5% 58.8% information is
12131295 10.01-20 22.8% 16.9% presented in the
>20 21.1% 10.5% single Figure of the
(1989- (1997- paper, depicting a
97) 2001) line graph of
median PSA
(measured between
diagnosis and
primary treatment)
for patients with
“low” or
“intermediate” risk
cancer.
4
Cooperberg CaPSURE <4 10.7% 11.2% 12.9% P<0.001
2003 4-10 37.2% 54.8% 63.2% (Mantel-Haenszel
14610406 10-20 25.2% 19.5% 15.8% test for trend)
>20 27.0% 14.5% 8.1%
(1989- (1996- (1999-
92) 99) 2002)
67
Cooperberg CaPSURE 0-4 25.5% 16.5% 17.2% NR Low-risk prostate
2004 15169800 4-10 74.6% 83.6% 82.8% cancer patients only
(1989- (1996- (1999- (n=1990)
92) 98) 2001)

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