Page 282 - An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer

Appendix Table C1.7. Tumor characteristics—stage
Author Database Stage groups 1980-84 1985- 1990-94 1995-99 2000-04 2005- Statistical Notes
Year 89 10 analysis
PMID
16
Mebane SEER Localized disease 64.4% 59.2% NR Data presented
1990 Regional disease 11.3% 11.9% only for Black
2258952 Distant disease 18.7% 18.9% and White
[White patients] (1980) (1985) individuals.
SEER Localized disease 59.2% 52.2% NR Data presented
Regional disease 9.4% 12.0% only for Black
Distant disease 29.2% 26% and White
[Black patients] (1980) (1985) individuals.

23
Dennis SEER Positive nodes 4% 2.6% 1.3% NR
2000 Not examined 80% (1992) NR
10679753 Lymph node status (1988) 75% (1996)
at diagnosis (1994)
31
Clegg SEER The study provided P<0.001 The cross-table
2002 a cross-table of the (chi-square suggests that the
12230422 proportion of test for stage x proportion of
patients with race x time patients with
localized/regional, period) distant disease
distant or unknown decreased and
cancer stage, by the proportion of
race and period of patients with
study (1975-87 and localized/regional
1988-97) disease
increased over
time, across all
racial/ethnic
groups studied.
37
Jani SEER AJCC stage Excluded AJCC
2007 0/I 53% 41% 53% 65% P=0.025 stage IV.
17505529 II 20% 25% 21% 22% (chi-square
III 26% 33% 25% 13% test)
(1984- (1989-93) (1994-98) (1999- RR=0.86 (CI
88) 2003) 0.70, 0.92)

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