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Early prediction of serious hyperbilirubinaemia

tested selectively. In the third study, readmission rates for phototherapy among DAT-tested
babies were 1.1% and among untested babies were 0.9%.

GDG translation from evidence
There is no good-quality prospective comparative study assessing the impact of universal DAT.
EL III studies found no significant difference between universal and selective screening or
between babies who received a DAT and those who had not received the test.

Recommendation – 4.2 Tests that do not predict significant hyperbilirubinaemia
Do not use any of the following to predict significant hyperbilirubinaemia
• umbilical cord blood bilirubin level
• end-tidal carbon monoxide (ETCOc) measurement
• umbilical cord blood direct antiglobulin test (DAT) (Coombs’ test).

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