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Introduction





                         gestational age.  There is a need for more uniform, evidence-based practice, and for consensus-
                                      1
                         based practice where such evidence is lacking, hence the importance of this guideline.

              2.2        Aim of the guideline

                         Clinical guidelines have been defined as ‘systematically developed statements  which assist
                         clinicians and patients in making decisions about appropriate treatment for specific conditions’.
                                                                                                           2
                         This clinical guideline concerns the management of neonatal jaundice in babies from birth up to
                         28 days of age.
                         This guideline has been developed with the aim of providing guidance on:
                         ●  recognition and assessment
                         ●  prediction of later significant hyperbilirubinaemia and adverse sequelae
                         ●  treatment
                         ●  information and education for parents/carers of babies with jaundice.


              2.3        Areas outside the remit of the guideline

                         This guideline does not address:
                         ●  primary prevention of jaundice
                         ●  jaundice that requires surgical treatment to correct the underlying cause
                         ●  management of babies with conjugated hyperbilirubinaemia, although we consider the
                           importance of identifying conjugated hyperbilirubinaemia.

              2.4        Who has developed the guideline


                         The  guidance was developed by a multi-professional  and lay  working  group (the Guideline
                         Development Group or GDG) convened by the National Collaborating Centre for Women's and
                         Children's Health (NCC-WCH). Membership included:
                         ●  two neonatologists (one as Chair)
                         ●  two midwives
                         ●  one general practitioner
                         ●  one paediatrician
                         ●  one pathologist
                         ●  one specialist nurse
                         ●  one community nurse
                         ●  one health visitor
                         ●  two patient/carer members.
                         Staff from the  NCC-WCH  provided methodological support for the guidance development
                         process, undertook systematic searches, retrieved and appraised the evidence, and  wrote
                         successive drafts of the guidance.
                         One external adviser was appointed by the GDG to advise on pharmacological interventions.
                         All GDG members' and external advisers' potential  and actual conflicts of interest  were
                         recorded on declaration forms provided by  NICE (summarised in Appendix B). None of the
                         interests declared by  GDG members constituted a material conflict of interest that would
                         influence recommendations developed by the GDG.

              2.5        Related NICE guidance


                         ●  Diabetes in pregnancy: management of diabetes and its complications from pre-conception to
                           the postnatal period. NICE clinical guideline 63 (2008). Available from
                           www.nice.org.uk/CG63
                         ●  Antenatal care: routine care for the healthy pregnant woman. NICE clinical guideline 62
                           (2008). Available from www.nice.org.uk/CG62

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