Page 119 - 16Neonatal Jaundice_compressed

Formal assessment for the causes of neonatal hyperbilirubinaemia

Table 6.1 Results of studies investigating the causes of jaundice at various levels of serum bilirubin
Country Criteria Preterm (%) Age (days) BF (%) Associated pathology
Blood group incompatibility G6PD deficiency Infection Idiopathic/no known cause
n N (%) n N (%) n N (%) n N (%)
Serum bilirubin less than 255 micromol/litre
Nigeria > 170 0–10 180 424 42.5 229 424 54 60 424 14.1 39 424 9.2
82
Nigeria > 170 0–10 11 40 27.5 13 40 32.5 34 40 85 3 40 7.5
83
Nigeria > 205 25.6 43 150 28.7 109 327 33.3 38 217 17.5
85
India > 170 30 100 30 4 100 4
86
87
India > 205 14 9 50 18 2 50 4 7 50 14
India > 205 16.7 102 454 24.5 23 454 5.1
84
Pakistan PT 13 113 869 13 20 869 2.3 165 869 19
88
Australia > 154 36.3 794 6129 12.9 51 6129 0.8 198 6129 3.2
89
90
China > 170 3.6 0–10 414 1811 22.9 241 1811 13.4 680 1811 37.5
Serum bilirubin between 255 micromol/litre and 399 micromol/litre
India > 255 18.5 0–15 63 24 92 26.1 4 92 4.3 18 92 19.6
91
Nigeria > 170 24 102 23.5 41 102 40.2 57 102 55.9
92
93
Israel > 306 0 0–10 95.2 0 21 0 2 21 9.5 0 21 0
Nigeria > 255 16 0–7 28 125 22.4 49 125 39.2 1 125 0.8 35 125 28
94
95
Papua New Guinea > 255 10 100 12 50 24 11 50 22 8 50 16 19 50 38
Singapore > 255 78 270 28.9 18 270 6.7
96
Singapore > 221 6.6 43 181 23.8 4 181 2.2
97
Taiwan > 255 0–10 62 196 31.6 43 196 21.9 10 196 5.1 53 196 27
98
Turkey 359 220 624 35.3 24 624 3.8 36 624 5.7
99
Iran 100 ICD 100 22 376 5.8 8 376 2.1 59 376 15.7
UAE 101 Chart 26 0–6 23 85 27 8 85 9.4
Saudi Arabia 102 > 255 23 211 10.9 64 211 30.3 4 411 1.9
Serum bilirubin> 400 micromol/litre or exchange transfusion
China ET 3.6 0–10 157 581 27 130 581 22.4
90
Singapore ET 18 46 39.1 2 46 4.3 8 46 17.4 6 46 13
96
84
India ET 39 66 59.1 11 66 16.7

89