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Diarrhoea and vomiting caused by gastroenteritis in children under 5 years




              Diarrhoea and vomiting in children                         Fluid management




             Fluid management



                                           Assess dehydration (see Table 4.6)


                                                 Clinical dehydration                 Clinical shock
                   No clinical                       (including                        suspected or
                  dehydration
                                                  hypernatraemic)                       confirmed


             Preventing dehydration          Oral rehydration therapy (ORT)           IVT for shock
              • Continue                 • Give 50 ml/kg low osmolarity ORS        • Give rapid
                                                 5
                breastfeeding and          solution over 4 hours, plus ORS            intravenous infusion
                other milk feeds.          solution for maintenance, often and        of 20 ml/kg 0.9%
                                                                                      sodium chloride
              • Encourage fluid            in small amounts.                          solution.
                intake.                  • Continue breastfeeding.                 • If child remains
              • Discourage fruit juices  • Consider supplementing with usual fluids   shocked repeat
                and carbonated             (including milk feeds or water, but not    infusion and
                drinks (especially in      fruit juices or carbonated drinks) if a    consider other
                children at increased      child without red flag symptoms or signs   causes of shock.
                risk of dehydration).      (see Table 4.6) refuses to take sufficient  • If child remains
              • Offer low osmolarity       quantities of ORS solution.                shocked after a
                                                                                      second infusion,
                          5
                ORS solution as          • Consider giving ORS solution via a         consider consulting
                supplemental fluid         nasogastric tube if a child is unable to   a paediatric
                if at increased risk       drink it or vomits persistently.           intensive care
                of dehydration.          • Monitor the response to ORT regularly.     specialist.

                                         • Clinical evidence of deterioration and
                                           red flag symptoms/signs (see Table 4.6) or  Symptoms/signs
                                         • child vomits ORS solution persistently.   of shock resolve


                                                  IVT for rehydration
                                   6
              • Give an isotonic solution for fluid deficit replacement and maintenance.
              • Add 100 ml/kg for children who were initially shocked, or 50 ml/kg for children who were not initially shocked,
                to maintenance fluid requirements.
              • Monitor the clinical response.
              • Measure plasma sodium, potassium, urea, creatinine and glucose at the start, monitor regularly, and change
                fluid composition or rate of administration if necessary.
              • Consider intravenous potassium supplementation when plasma potassium level is known.
              • Continue breastfeeding if possible.
              • If hypernatraemic at presentation:
                – obtain urgent expert advice on fluid management
                                   6
                – use an isotonic solution for fluid deficit replacement and maintenance
                – replace the fluid deficit slowly (typically over 48 hours)
                – aim to reduce the plasma sodium at less than 0.5 mmol/l per hour.



              • During IVT, attempt to introduce ORT early and gradually. If tolerated, stop IVT and complete rehydration with ORT.



             5 240–250 mOsm/l. The ‘BNFC’ 2008 edition lists the following products with this composition: Dioralyte, Dioralyte Relief,
             Electrolade and Rapolyte.
             6  Such as 0.9% sodium chloride, or 0.9% sodium chloride with 5% glucose.


             NICE clinical guideline 84                                            Quick reference guide  9


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